Table 2 Results from the six randomised studies on PFO closure in cryptogenic stroke (data from 10, 12, 21)
From: Cryptogenic stroke and patent foramen ovale (abridged and translated version)
| Parameters | Closure I | PC Trial | RESPECT | REDUCE | CLOSE | Defense PFO | |
|---|---|---|---|---|---|---|---|
| Stroke (%) | M | 3.1 | 2.4 | 5.8 | 5.4 | 6.0 | 10.5 |
| Stroke (%) | C | 2.9 | 0.5 | 3.6 | 1.4 | 0.0 | 0 |
| TIA (%) | M | 4.1 | 3.3 | 4.8 | – | – | 2.0 |
| TIA (%) | C | 3.1 | 2.5 | 3.4 | – | – | 0 |
| Death (%) | M | 0 | 0 | 2.2 | 0 | 0 | 0 |
| Death (%) | C | 0 | 1.0 | 1.4 | 0.5 | 0 | 0 |