Table 3 Results of meta-analyses for PFO closure in cryptogenic stroke
From: Cryptogenic stroke and patent foramen ovale (abridged and translated version)
Author | Studies | N | Endpoint | 95% CI | P | |
|---|---|---|---|---|---|---|
Abo Salem et al. [12] | 5 | 3627 | Stroke | RR 0.48 | 0.3–0.7 | 0.001 |
De Rosa et al. [13] | 4 | 3216 | Stroke and TIA | RD −0.029 | −0.050 - -0.007 | 0.008 |
Ntaios et al. [11] | 5 | 3627 | Stroke | OR 0.43 | 0.21–0.90 | NI |
Shah et al. [14] | 4 | 2892 | Stroke | RD −0.032 | −0.050 - -0.014 | 0.011 |
Saver et al. [24] | 6 | 3560 | Stroke | HR 0.30 | 0.13–0.68 | 0.004 |
Ahmad et al. [15] | 5 | 3440 | Stroke | HR 0.32 | 0.13–0.82 | 0.018 |