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Table 7 EULAR/ACR-Classification Criteria for SLE (2018)

From: Cerebral involvement in systemic vasculitides

Scoring points of organ manifestations

 Constitutional symptoms

  Fever

2

 Skin

  Non-scarring alopecia

2

  Oral ulcers

2

  Subacute-cutaneous or discoid LE

4

  Acute cutaneous LE

6

 Arthritis

  Synovitis in ≥2 joints or pressure pain in ≥2 joints with morning stiffness ≥30 min

6

 Neurology

  Delirium

2

  Psychosis

3

  Seizure

5

 Serositis

  Pleural or Pericardial extravasation

5

  Acute pericarditis

6

 Hematology

  Leukopenia

3

  Thrombopenia

4

  Autoimmunohemolysis

4

 Kidneys

  Proteinuria > 0.,5 g/24 h

4

  Lupus nephritis (histol.) Type II, V

8

  Lupus nephritis (histol.) Type III, IV

10

Scoring points of immunologic findings

 Antiphospholipid antibodies

  aCL > 40 GPL or aß2GPI > 40 GPL or LA +

2

 Complement

  C3 or C4 reduced

3

  C3 and C4 reduced

4

 Specific auto-antibodies

  a-ds-DNS-Ab

6

  a-Sm-Ab

6

  1. Prerequisite: ANA (HEp2-IFT) ≥ 1:80.  Classification as SLE starting at 10 points.Only the highest score within each domain is used for the total score. A criterion is not counted if another, more likely cause is present (such as for example infection, NPL, medications or other diseases). Criteria must not be concurrently present, a criterion is met if it was present in the documentation on one occasion, at least one criterion must be currently present