Table 1 Overview of commercially available software applications for automated and semi-automated medical image analysis for acute stroke diagnostics (Descriptions are based on information provided by the companies on their official websites. Some companies also offer algorithm outside the ischemic stroke field; we listed them for completion but do not further discuss those)

Aidoc

Aidoc Head

triages stroke patients using non-contrast CT scans by flagging suspected intracranial haemorrhages and highlights cases that require immediate attention in worklist

Apollo Medical Imaging Technology

CT Perfusion: Stroke

CTP stroke module is a part of MIStar software package. It generates brain perfusion maps using deconvolution algorithms together with Apollo’s noise reduction and motion artefact correction technologies

DSC-MRI: Stroke

DSC-MRI perfusion module is a part of MIStar software. It features both parametric curve analysis and deconvolution algorithm for perfusion maps with easy identification of arterial input function

Brainomix

e-ASPECTS

assess the ASPECTS^a score and volume of ischemia in non-contrast CT images

e-CTA

standardizes the assessment of collaterals in CTA scans

inferVISION

AI-CT (head)

gets information about type of stroke (haemorrhagic or ischemic), determines location, volume and severity of haemorrhagic strokes

iSchemaView

RAPID CTA

automatically provides CTA maps and identifies brain regions with reduced blood vessel density

RAPID CTP

provides cerebral perfusion maps

RAPID MRI

provides fully automated diffusion and perfusion maps

RAPID ASPECTS

automatically identifies and scores regions with early ischemic changes using ASPECTS

JLK Inspection

JBS-01 K

Ischemic stroke subtype (TOAST^b) classification solution based on MR images and clinical information data

JBS-02 K

Ischemic stroke severity (NIHSS^c) prediction solution based on MR images, clinical information data and 3D hybrid artificial neural network technology

JBS-03 K

Ischemic stroke prognosis (3-month mRS^d) prediction solution based on MR images, clinical information data and 3D hybrid artificial neural network technology

JBS-04 K

Haemorrhagic stroke detection and classification solution based on CT images and 3D hybrid artificial neural network technology

JBS-05 K

Hyperacute ischemic stroke detection solution based on CT images and clinical information data

JBS-06 K

Hyperacute ischemic stroke detection solution based on MRI, clinical information data and 3D hybrid artificial neural network technology

JBA-01 K

Aneurysm detection solution based on MR angiography, clinical information data and 3D hybrid artificial neural network technology

Max-Q AI

AccipioDx

diagnostic tool that rules out the presence of intracranial haemorrhage in non-contrast CT scans

mbits

mRay-Modul veocore

Perfusion analysis tool

Nico.lab

StrokeViewer

provides analysis of relevant biomarkers from stroke imaging (NCCT, CTA, dynamic CTA and follow-up imaging). The following have been clinically validated: Haemorrhage detection and quantification, thrombus identification and evaluation, collateral assessment, follow-up infarct volume quantification, ASPECTS (in development)

Olea Medical

Olea Sphere

automatically computes core, penumbra and mismatch ratio in CT and MR perfusion images

Qure.ai

qER

detects critical abnormalities such as bleeds, fractures mass effect and midline shift, localizes them and quantifies their severity in head CT

qQuant

suite of quantification and progression monitoring products for CT and MRI scans (e.g. brain tumour volume)

Viz.ai

Viz LVO

automatically identifies and triages suspected large vessel occlusion (LVO) strokes

Viz CTP

automatically analyse CT perfusion images

Zebra Medical Vision

AI1

All-In-One (AI1) Application with included algorithm for intracranial haemorrhage detection. AI1 detects also other medical conditions like low bone mineral density, vertebral fractures and more