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Table 1 Inclusion and exclusion criteria for patient and control selection

From: Validation of a German version of the Cerebellar Cognitive Affective/ Schmahmann Syndrome Scale: preliminary version and study protocol

Group

Inclusion criteria

Exclusion criteria

General

- Age ≥ 18 years

- German-speaking (primary language)

- Informed consent

- Alcohol or drug abuse

- Intake of centrally acting drugs (other than low-dose antidepressants)

- Consuming diseases

- Poor health condition

- Persons under legal supervision

Patients

- General inclusion criteria

- General exclusion criteria

- Severe primary psychiatric disorders

Degenerative Cerebellar Disorders

Cer-pure

Disorders primarily affecting the cerebellum

- SAOA

- EA1 and EA2

- SCA6

- SCA8

- SCA14

- ANO10

- Post-inflammatory cerebellar degeneration

Cer-plus

Disorders with relevant extracerebellar involvement

- MSA-C

- all other hereditary ataxias including: SCA1, 2, 3, Friedreich’s ataxia, early onset cerebellar ataxias

Focal Cerebellar Lesions

Cer-pure/ cer-plus

- Cerebellar stroke

- Cerebellar hemorrhage

- Cerebellar tumor

- Cerebellar surgical lesion

Controls

- General inclusion criteria

- General exclusion criteria

- Neurological and psychiatric disorders

Pretesting Subjects

- General inclusion criteria

- General exclusion criteria

- Neurologists and psychologists that were involved in the development of the German CCAS Scales

  1. Abbreviations: Cer-pure Isolated Cerebellar Disease/ Lesion, Cer-plus Cerebellar Plus Disease/ Lesion, SAOA Sporadic Adult Onset Ataxia, EA1 Episodic Ataxia Type 1, EA2 Episodic Ataxia Type 2, SCA1, 2, 3, 6, 8, 14 Spinocerebellar Ataxia Type 1, 2, 3, 6, 8, 14, ANO10 Spinocerebellar Ataxia, Autosomal-Recessive Type 10, MSA-C Multisystem Atrophy Cerebellar Type, CCAS Cerebellar Cognitive Affective/ Schmahmann Syndrome