Table 1 Baseline characteristics of patients with ischemic stroke and unknown symptom onset
Variable | Prior APT (n = 164) | No prior APT (n = 339) | P Value |
|---|---|---|---|
Age, mean (SD), years | 70.3 (8.2) | 62.8 (12.1) | < 0.001 |
Female sex, No. (%) | 60 (36.6) | 118 (34.8) | 0.692 |
Time between last seen well and symptom recognition, median (IQR), hours | 7.52 (5.00–8.50) | 7.00 (4.67–9.50) | 0.085 |
Medical history/risk factors, No. (%) | |||
Arterial hypertension | 120 (73.2) | 146 (43.1) | < 0.001 |
Diabetes mellitus | 44 (26.8) | 38 (11.2) | < 0.001 |
Hypercholesterolemia | 98 (59.8) | 80 (23.6) | < 0.001 |
Atrial fibrillation | 27 (16.5) | 32 (9.4) | 0.010 |
History of ischemic stroke | 52 (31.7) | 16 (4.7) | < 0.001 |
History of TIA | 17 (10.4) | 6 (1.8) | < 0.001 |
Current or former smoker | 94 (58) | 162 (50) | 0.009 |
NIHSS score, median (IQR) | 6 (4–12) | 5 (4–9) | 0.104 |
DWI lesion volume at baseline, median (IQR), ml | 2.28 (0.80–9.61) | 2.23 (0.70–7.70) | 0.506 |