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Table 1 Baseline characteristics of patients with ischemic stroke and unknown symptom onset

From: Safety and efficacy of intravenous thrombolysis in stroke patients on prior antiplatelet therapy in the WAKE-UP trial

Variable Prior APT (n = 164) No prior APT (n = 339) P Value
Age, mean (SD), years 70.3 (8.2) 62.8 (12.1) <  0.001
Female sex, No. (%) 60 (36.6) 118 (34.8) 0.692
Time between last seen well and symptom recognition, median (IQR), hours 7.52 (5.00–8.50) 7.00 (4.67–9.50) 0.085
Medical history/risk factors, No. (%)
 Arterial hypertension 120 (73.2) 146 (43.1) <  0.001
 Diabetes mellitus 44 (26.8) 38 (11.2) <  0.001
 Hypercholesterolemia 98 (59.8) 80 (23.6) <  0.001
 Atrial fibrillation 27 (16.5) 32 (9.4) 0.010
 History of ischemic stroke 52 (31.7) 16 (4.7) <  0.001
 History of TIA 17 (10.4) 6 (1.8) <  0.001
 Current or former smoker 94 (58) 162 (50) 0.009
NIHSS score, median (IQR) 6 (4–12) 5 (4–9) 0.104
DWI lesion volume at baseline, median (IQR), ml 2.28 (0.80–9.61) 2.23 (0.70–7.70) 0.506
  1. SD standard deviation, IQR interquartile range, TIA transient ischemic attack, NIHSS National Institute of Health Stroke Scale, DWI diffusion weighted imaging