Fig. 3From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)IgG band patterns. Five different patterns can be found, with patterns 2 and 3 indicating intrathecal synthesis, as shown in Fig. 3: Type 1: Normal finding. Type 2: Isolated OCB in the CSF. Type 3: Identical OCB in cerebrospinal fluid and serum, additionally isolated OCB in the CSF. Type 4: OCB with identical (mirror image) distribution in the CSF and serum. Type 5: Monoclonal bands (usually identical distribution in the CSF and serum) as an indication of systemic gammopathy [51]Back to article page