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Table 11 Diagnostic criteria for PML (according to [20])

From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)

Certainty of PML diagnosis Clinical features MRI JCPyV-PCR
Definite + + +
Probable + +
+ +
Possible + + −/ND
+
Not PML
+
+
  1. ND Not determined