Table 15 CSF parameter of AE
From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)
| Antigen | Pleocytosis in CSF (%) | Dysfunction of the blood/CSF barrier (%) | CSF-specific OCBs (%) | Detection of disease-specific antibody | References | |
|---|---|---|---|---|---|---|
| Serum | CSF | |||||
| NMDAR | 70-90 | ~ 30 | 50-70 | (+) | + | [33, 81] |
| AMPAR | 50-70 | 40-60 | ~ 30 | +/(+) | + | [71, 93] |
| GABAAR | 40-70 | 20-70 | 20-30 | + | + | [141, 158] |
| GABABR | 60-70 | 30-40 | 60 | + | + | [62, 70, 91, 134] |
| GlyR | 0-40 | ~ 50 | 20-30 | + | + | [29, 115] |
| LGI1 | 10-20 | 20-30 | < 10 | + | (+) | [52, 77, 82, 101, 156, 157] |
| CASPR2 | 30-70 | n.b. | ~ 40 | + | (+) | [22, 52, 94] |
| DPPX | 20-60 | ~ 30 | ~ 30 | + | + | [13, 65, 170] |
| IgLON5 | 0-30 | 30-50 | 0-10 | + | + | [53, 74, 151] |
| GAD65 | 0-20 | 10-30 | 0-70 | + | + | [15, 46, 73, 112] |