Table 17 Expected patterns of the CSF biomarkers in different neurodegenerative disorders
From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)
Ab42 or Ab42/40 | Tau | pTau | |
|---|---|---|---|
Alzheimer’s disease | ↓ | ↑ | ↑ |
Vascular Dementia | ↔ | (↑) | (↑) |
bvFTD | ↔ | (↑) | (↑) |
nf-avPPA | ↔ | (↑) | (↑) |
svPPA | ↔ | ↔ | ↔ |
lvPPA | ↓ | ↑ | ↑ |
CBD | (↔) | (↑) | (↑) |
DLB | (↔) | (↑) | (↑) |