Intervention
|
Treatment with intravenous thrombolysis, % (n)
|
55.6% (1393)
|
67.7% (42)
|
.069
|
Anesthesia, % (n)
|
Conscious sedation
|
30.2% (733)
|
21.0% (13)
|
.281
|
Beginning with conscious sedation, switch to general anesthesia
|
3.7% (90)
|
4.8% (3)
|
Primary general anesthesia
|
66.1% (1602)
|
74.2% (46)
|
Number of passages, median (IQR), n
|
2 (1-3), n = 2527
|
2 (1-3), n = 62
|
.377
|
Intra-arterial medication, % (n)
|
15.6% (387)
|
34.4% (21)
|
<.001
|
Additional heparin bolus given, % (n)
|
13.3% (303)
|
27.1% (16)
|
.006
|
Concomitant stenting of > 70% ipsilateral extracranial ICA stenosis (if present), % (n)
|
70.0% (231)
|
64.3% (18)
|
.527
|
Time intervals
|
Known symptom onset
|
Time from symptom onset to flow restoration - min, median (IQR), n
|
245 (190-322), n = 1553
|
322 (233-435), n = 46
|
<.001
|
Unknown symptom onset
|
Time from last-seen-well to flow restoration - min, median (IQR), n
|
520 (352-833), n = 974
|
466 (385-524), n = 16
|
.657
|
Known and unknown symptom onset
|
Time from admission to i.v. thrombolysis - min, median (IQR), n
|
21 (-76-35), n = 2527
|
17 (-71-30), n = 62
|
.518
|
Time from admission to groin puncture - min, median (IQR), n
|
71 (46-104), n = 2527
|
90 (56-126), n = 62
|
.019
|
Time from groin puncture to flow restoration - min, median (IQR), n
|
70 (45-100), n = 2527
|
98 (67-136), n = 62
|
<.001
|