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Table 5 Functional outcome

From: Mechanical thrombectomy in patients with cervical artery dissection and stroke in the anterior or posterior circulation – a multicenter analysis from the German Stroke Registry

 

No CAD, n = 2527

CAD, n = 62

Parameter estimate

(95% CI)a

Pcrude

Padj

After 24 h

 NIHSS after 24 h, median (IQR), n

10 (4-20), n = 2527

6.5 (2-15), n = 62

.b, c

-1.39 (-4.85-2.06)d

.010b

.428d

 mRS score after 24 h, % (n)

  0

2.8% (60)

10.5% (6)

0.60 (0.13-1.07)b

- 0.04 (- 0.71-0.63)d

.013b

.901d

  1

6.1% (133)

12.3% (7)

  2

8.7% (190)

7.0% (4)

  3

13.1% (286)

14.0% (8)

  4

18.0% (391)

14.0% (8)

  5

50.5% (1100)

42.1% (24)

  6

0.8% (17)

0.0% (0)

   ≤ 2

17.6% (383)

29.8% (17)

-0.69 (-1.27 - -0.11)b

0.35 (- 0.60-1.30)d

.020b

.472d

At discharge

 NIHSS at discharge, median (IQR), n

6 (2-13), n = 2527

3 (0-10), n = 62

.b, c

0.23 (-3.05-3.52)d

.003b

.889d

 mRS score at discharge, % (n)

  0

8.2% (202)

20.0% (12)

0.95 (0.50-1.40)b

0.26 (-0.34-0.86)d

<.001b

.403d

  1

12.0% (296)

21.7% (13)

  2

11.6% (286)

10.0% (6)

  3

13.6% (336)

16.7% (10)

  4

17.0% (420)

10.0% (6)

  5

21.7% (534)

16.7% (10)

  6

15.8% (390)

5.0% (3)

   ≤ 2

31.8% (784)

51.7% (31)

-0.83 (-1.34 - -0.32)b

0.20 (-0.55-0.96)d

.002b

.599d

After 90 days

 mRS score after 90 days, % (n)

    

  0

11.7% (260)

18.2% (10)

1.06 (0.59-1.53)b

0.29 (-3.5-0.94)d

<.001b

.372d

  1

14.3% (318)

32.7% (18)

  2

10.4% (232)

20.0% (11)

  3

12.4% (275)

5.5% (3)

  4

12.7% (283)

9.1% (5)

  5

10.2% (226)

9.1% (5)

  6

28.4% (632)

5.5% (3)

   ≤ 2

36.4% (810)

70.9% (39)

-1.45 (-2.04 - -0.86)b

-0.74 (-1.59-0.10)d

<.001b

.086d

  1. aParameter estimates and 95% confidence intervals derived from univariate general linear (NIHSS score), ordinal (mRS distributions), or binary (dichotomized mRS score) regression models; the reference category is formed by patients with CAD. b Unadjusted models c No parameter estimate derived from from Mann-Whitney test. d Analysis adjusted for age, gender, pre-stroke modified Rankin scale score, medical history, prior medication, Alberta Stroke Program Early CT Score, and location of occluded vessel. CAD stands for cervical artery dissection; IQR, interquartile range; mRS, modified Rankin scale; NIHSS, National Institutes of Health Stroke Scale