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Table 1 Characteristics of patients

From: N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial

  DMG Placebo
Baseline (n = 20) 12 months (n = 17) Baseline (n = 10) 12 months (n = 9)
Age (years) 54.9 ± 5.7   52.1 ± 5.9  
Sex (M/F) 6/14   1/9  
SPMS (M/F) 4/10   0/8  
PPMS (M/F) 2/4   1/1  
Weight (kg) 75.8 ± 16.3   75.6 ± 21.3  
Height (cm) 167.6 ± 10.1   166.4 ± 7.1  
Disease duration (years) 13.8 ± 9.3   18.8 ± 10.0  
Study variables
 EDSS (score) 4.6 ± 2.0 (5.3) 4.5 ± 2.0 (4.5) 5.2 ± 1.5 (6.0) 5.3 ± 1.7 (6.0)
 FIS-D (score) 85.8 ± 26.8 (86.5) 76.0 ± 35.0 (86.0) 73.3 ± 25.7 (73.5) 81.6 ± 21.5 (89.0)
 PASAT (score) 40.6 ± 8.8 (39.0) 41.4 ± 12.0 (36.0) 35.6 ± 7.0 (34.0) 44.2 ± 9.7 (42.0)
 Gait velocity (km/h) 2.5 ± 1.1 2.5 ± 1.2 2.6 ± 0.7 2.6 ± 0.8
 Stride length (m) 0.50 ± 0.1 0.52 ± 0.2 0.49 ± 0.1 0.55 ± 0.2
 Stride variability (%) 4.2 ± 2.7 4.4 ± 4.5 12.9 ± 22.9 11.7 ± 17.1
 6 min Walking Test (m) 259.9 ± 141.8 267.2 ± 135.6 268.6 ± 80.5 277.3 ± 84.5
 Knee angle stance (left/2 + right/2)(°) 16.3 ± 4.9 16.4 ± 4.4 17.8 ± 7.5 17.5 ± 6.1
 Knee angle swing (left/2 + right/2)(°) 48.8 ± 10.5 49.1 ± 9.2 47.8 ± 7.7 49.7 ± 6.7
  1. SPMS secondary progressive MS, PPMS primary progressive MS, EDSS Expanded Disability Status Scale, FIS-D Fatigue Impact Scale, PASAT Paced Auditory Serial Addition Test, mean ± sd () = median