Fig. 3

Generic quality of life (EQ-5D) among TSC patients compared with patients with other chronic disorders. Comparison of quality of life (QoL), as assessed by the EuroQoL-5 dimensions (EQ-5D), between a study (Lucas et al., [38]) including 69 patients with severe asthma and 249 patients with severe migraine and our cohort of tuberous sclerosis complex (TSC) individuals, stratified by the number of TSC manifestations. A large difference in QoL between lightly and more severely affected TSC individuals is evident, with more severely affected individuals exhibiting QoL similar to patients with other severe chronic disorders