Factors influencing the detection of treatable epileptogenic lesions on MRI. A randomized prospective study

Table 2 No of correctly read MRIs stratified by lesion category, provision of focus hypothesis, and reader specialty. P-values refer to the difference of detecting the lesion constellation with or without focus hypothesis for all readers

MRI reader speciality	Neurology		Epileptology		Radiology		Neuroradiology		total		p-value
focus hypothesis provided	No	yes	No	yes	no	yes	no	yes	no	yes
Focal cortical dysplasia
Correctly identified lesions/	7	16	9	9	3	6	6	9	25	40	0.03
Total scans	47	47	22	22	20	20	21	21	110	110	0.03
	15%	34%	41%	41%	15%	30%	29%	43%	22.7%	36.4%
Hippocampal sclerosis or limbic encephalitis
Correctly identified lesions/	19	33	14	19	7	16	15	18	55	86	< 0.001
Total scans	47	48	22	22	20	20	21	20	110	110	< 0.001
	40%	69%	64%	86%	35%	80%	71%	90%	50.0%	78.2%
Low grade epilepsy associated tumor
Correctly identified lesions/	34	36	20	15	18	19	19	21	91	91	0.88
Total scans	48	48	22	22	20	20	20	21	110	111	0.88
	71%	75%	91%	68%	90%	95%	95%	100%	82.7%	82.0%
Nodular (periventricular) heterotopia
Correctly identified lesions/	6	9	9	10	7	5	11	11	33	35	0.77
Total scans	47	48	22	22	20	20	21	20	110	110	0.77
	13%	19%	41%	45%	35%	25%	52%	55%	30.0%	31.8%
Gliotic scar or hemosiderin or cavernoma
Correctly identified lesions/	24	28	16	18	18	17	18	18	76	81	0.46
Total scans	48	47	22	22	20	20	20	21	110	110	0.46
	50%	60%	73%	82%	90%	85%	90%	86%	69.1%	73.7%
Nonlesional
Correctly read/	25	37	18	14	15	10	13	16	71	77	0.39
Total scans	48	48	22	22	20	20	21	21	111	111	0.39
	52%	77%	82%	64%	75%	50%	62%	76%	64.0%	69.4%
All scans
Correctly interpreted/	115	159	86	85	68	73	82	93	351	410
Total scans	285	286	132	132	120	120	124	124	661	662
	40.4%	55.6%	65.2%	64.4%	56.7%	60.8%	66.1%	75.0%	53.1%	61.9%

ISSN: 2524-3489