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Table 2 No of correctly read MRIs stratified by lesion category, provision of focus hypothesis, and reader specialty. P-values refer to the difference of detecting the lesion constellation with or without focus hypothesis for all readers

From: Factors influencing the detection of treatable epileptogenic lesions on MRI. A randomized prospective study

MRI reader speciality Neurology Epileptology Radiology Neuroradiology total p-value
focus hypothesis provided No yes No yes no yes no yes no yes  
Focal cortical dysplasia
 Correctly identified lesions/ 7 16 9 9 3 6 6 9 25 40 0.03
 Total scans 47 47 22 22 20 20 21 21 110 110
  15% 34% 41% 41% 15% 30% 29% 43% 22.7% 36.4%  
Hippocampal sclerosis or limbic encephalitis
 Correctly identified lesions/ 19 33 14 19 7 16 15 18 55 86 < 0.001
 Total scans 47 48 22 22 20 20 21 20 110 110
  40% 69% 64% 86% 35% 80% 71% 90% 50.0% 78.2%  
Low grade epilepsy associated tumor
 Correctly identified lesions/ 34 36 20 15 18 19 19 21 91 91 0.88
 Total scans 48 48 22 22 20 20 20 21 110 111
  71% 75% 91% 68% 90% 95% 95% 100% 82.7% 82.0%  
Nodular (periventricular) heterotopia
 Correctly identified lesions/ 6 9 9 10 7 5 11 11 33 35 0.77
 Total scans 47 48 22 22 20 20 21 20 110 110
  13% 19% 41% 45% 35% 25% 52% 55% 30.0% 31.8%  
Gliotic scar or hemosiderin or cavernoma
 Correctly identified lesions/ 24 28 16 18 18 17 18 18 76 81 0.46
 Total scans 48 47 22 22 20 20 20 21 110 110
  50% 60% 73% 82% 90% 85% 90% 86% 69.1% 73.7%  
Nonlesional
 Correctly read/ 25 37 18 14 15 10 13 16 71 77 0.39
 Total scans 48 48 22 22 20 20 21 21 111 111
  52% 77% 82% 64% 75% 50% 62% 76% 64.0% 69.4%  
All scans
Correctly interpreted/ 115 159 86 85 68 73 82 93 351 410  
Total scans 285 286 132 132 120 120 124 124 661 662  
  40.4% 55.6% 65.2% 64.4% 56.7% 60.8% 66.1% 75.0% 53.1% 61.9%