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Table 2 Overview of selected clinical and diagnostic findings in the presented case and literature review

From: Paraneoplastic encephalomyeloradiculits with multiple autoantibodies against ITPR-1, GFAP and MOG: case report and literature review

  Case NMDA + ITPR1 + GFAP
(i.e. [1])
ITPR1
(i.e. [1])
GFAP
(i.e. [6])
MOG
(i.e. [8, 9])
Clinical symptoms
Subacute onset + + + + +
Prior infection +
(vaginal herpes)
+   + +
Meningism +    +  
Confusion + +   +  
Para/Tetraparesis + + + +  
Sensory loss + + + +  
Ataxia +   + +  
Nystagmus +   +   
Seizures + + + +  
Autonomic symptoms +
(neccessary pace maker)
  + +  
Vision deficits     + +
Neuropathy    +   
Areflexia +   +   
Diagnostic Examinations
Signs of meningitis in MRI +    +  
T2w lesions in cerebral MRI +
(esp. parieto-occipital)
+
(esp. temporo-cerebellar)
  +
(esp. periventricular white matter)
+
(esp. deep grey matter involvement)
Spinal MRI +
(spinal cord swelling, edema)
+
(long myelitis)
+
(myelitis)
+
(myelitis)
+
(myelitis)
Tumor association (+)
(borderline tumor of left ovary)
- 41% tumor association
(no borderline known)
36% tumor association
(no borderline known)
Usually no tumor association