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Table 3 Statistical results concerning the histological evaluation of the reference thrombi and the emboli of stroke patients

From: Development and reliability of the histological THROMBEX-classification rule for thrombotic emboli of acute ischemic stroke patients

Reference thrombi

R1 (N = 11)/R2 (N = 8)

Histological evaluation

CARDIO

ARTERIO

Certain genesis of thrombi

 Cardiac (C)

4/3

1/0

 Arteriosclerotic (A)

2/1

4/4

Intraobserver reliability [%, (95% CI)]

 C: R1 (N = 5)/R2 (N = 3)

80 (28.4–99.5)/100 (29.2–95.0)

 A: R1 (N = 6)/R2 (N = 5)

66.7 (22.3–95.7)/80 (28.4–99.5)

 C + A: R1 (N = 11)/R2 (N = 8)

72.7/87.5

Interobserver reliability (N = 8)

 Agreement [%]

87.5

 κ (95% CI)

0.75 (0.31–1)

Emboli of stroke patients

 Intraobserver reliability [%/κ (95% CI)]

  R1 (N = 14)

92.9/0.81 (0.46–1)

  R2 (N = 22)

68.2/0.36 (− 0.02 to 0.75)

 Interobserver reliability (N = 123)

  Agreement [%]

69.9

  κ (95% CI)

0.39 (0.23–0.55)

  1. R1, rater I; R2, rater II; κ, Cohen’s kappa; CI, confidence interval