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Table 3 Statistical results concerning the histological evaluation of the reference thrombi and the emboli of stroke patients

From: Development and reliability of the histological THROMBEX-classification rule for thrombotic emboli of acute ischemic stroke patients

Reference thrombi
R1 (N = 11)/R2 (N = 8)
Histological evaluation
CARDIO ARTERIO
Certain genesis of thrombi
 Cardiac (C) 4/3 1/0
 Arteriosclerotic (A) 2/1 4/4
Intraobserver reliability [%, (95% CI)]
 C: R1 (N = 5)/R2 (N = 3) 80 (28.4–99.5)/100 (29.2–95.0)
 A: R1 (N = 6)/R2 (N = 5) 66.7 (22.3–95.7)/80 (28.4–99.5)
 C + A: R1 (N = 11)/R2 (N = 8) 72.7/87.5
Interobserver reliability (N = 8)
 Agreement [%] 87.5
 κ (95% CI) 0.75 (0.31–1)
Emboli of stroke patients
 Intraobserver reliability [%/κ (95% CI)]
  R1 (N = 14) 92.9/0.81 (0.46–1)
  R2 (N = 22) 68.2/0.36 (− 0.02 to 0.75)
 Interobserver reliability (N = 123)
  Agreement [%] 69.9
  κ (95% CI) 0.39 (0.23–0.55)
  1. R1, rater I; R2, rater II; κ, Cohen’s kappa; CI, confidence interval