Skip to main content

Table 2 Description of technique for angiographic nimodipine test

From: Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a neuroradiological method to help differentiate from primary central nervous system vasculitis

Insertion of a 4F sheath in Seldinger technique establishing a right femoral artery access under local anaesthesia
Diagnostic cerebral angiography from internal carotid arteries bilaterally, as well as from vertebral artery
If suspicious caliber irregularities are found in standard projections, acquisition of additional projections (e.g. 45° oblique)
Leave 4 F catheter (Tempo 4 F, VER 135°, Cordis Corporation, Miami Lakes, USA) in internal carotid or vertebral artery on the side of most prominent caliber irregularities
Dissolve 3 mg (15 ml) of Nimodipine (Nimotop®S, 10 mg/50 ml, BayerVital GmbH, Leverkusen, Germany) in 1000 ml isotonic NaCl
Infuse nimodipine at a rate of 3 mg per hour (via 3-way stopcock)
In case of known low blood pressure continous blood pressure monitoring is advisable
Take pictures in the same projection after 15, 30, 45 and 60 min. Patient's head should be fixed to ensure constant projection
Withdrawal of catheter and compression of the groin