Fig. 2

Transcranial Doppler sonography of a 14-year-old SCD-patient without stem cell transplantation. Measurements were taken in the middle cerebral artery (MCA). There was a long-term follow-up from 07/2016 to 03/2021 (see a–e). A total of 5 TCDs were performed. f Shows the time course of PSV (peak systolic velocity) and TAMX (time averaged maximum velocity, TAMMV). As abnormal blood flow velocities with a TAMX of 217 cm/s were derived in the TCD in 03/2020, we performed a control in short-term interval in 06/2020. Here, a TAMX/TAMMV of < 200 cm/s ("conditional") was shown again