Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease

Table 1 TAMMV without stem cell transplantation or before and after stem cell transplantation with overt stroke

Genotype	Acute stroke	TAMMV with/without HSCT	HSCT	TAMMV after HSCT
HbSS	x	Normal	x	–
HbSS	x	–	x	Normal
HbSS	x	–	x	Normal
HbSS	–	Conditional	x	Normal
HbSS	–	Conditional	x	–
HbSS	–	Normal	x	Normal
HbSß⁺-Thalassemia	–	Normal	x	–
HbSß⁺-Thalassemia	–	–	x	Normal
HbSS	–	Conditional	x	Conditional
HbSS	–	Conditional	x	–
HbSS	–	Normal	x	–
HbSS	–	Normal	x	–
HbSß⁺-Thalassemia	–	Normal	x	Normal
HbSS	x	Conditional	–	–
HbSß⁺-Thalassemia	–	Normal	–	–
HbSS	–	Normal	–	–
HbSS	–	Normal	–	–
HbSS	–	Conditional	–	–
HbSS	–	Conditional	–	–
HbSS	–	Conditional	–	–
HbSß⁺-Thalassemia	–	Normal	–	–
HbSSα-Thalassemia minima	–	Conditional	–	–
HbSSα-Thalassemia minima	–	Conditional	–	–
HbSSα-Thalassemia minima	–	Conditional	–	–
HbSSα-Thalassemia minor	–	Conditional	–	–
HbSC	–	Conditional	–	–

Normal TAMMV were defined as blood flow velocities < 170 cm/s. Conditional TAMMV were blood flow velocities between 170 and 200 cm/s

ISSN: 2524-3489