Characteristics | Recurrent SE | Group, diabetes | Group, no diabetes | p-value |
---|---|---|---|---|
Episodes | N = 74 | N = 27 | N = 47 |  |
Stop treatment with VPA | 19 (26%) | 6 (22%) | 13 (28%) | 0.606 |
Reason: adverse events* | 6 (8%) | 3 (11%) | 3 (6%) | 0.662 |
Reason: interaction of medication* | 5 (7%) | 1 (4%) | 4 (9%) | 0.647 |
Other reasons, no adverse events* | 8 (11%) | 2 (7%) | 6 (13%) | 0.702 |
Adverse events | ||||
Disturbance of consciousness* | 2 (3%) | 1 (4%) | 1 (2%) | 1.0 |
Thrombocytopenia* | 1 (1%) | 1 (4%) | 0 | 0.365 |
Parkinsonism* | 0 | 0 | 0 | / |
Elevation of liver enzymes* | 1 (1%) | 0 | 1 (2%) | 1.0 |
Bleeding* | 0 | 0 | 0 | / |
Others* | 2 (3%) | 1 (4%) | 1 (2%) | 1.0 |