Group | Patient # | Primary symptom/diagnosis | Secondary diagnosis | Weeks since COVID-19 infection | Age (years) | Gender | Neurological exam | cMRI | CSF |
---|---|---|---|---|---|---|---|---|---|
Persistent Post-COVID-19 headache | 1 | Headache | Migraine | 32 | 49 | Female | Normal | n.a | No inflammatory change |
2 | Headache | Recurrent syncopes | 16 | 23 | Female | Normal | Normal | No inflammatory change | |
3 | Headache | None | 52 | 46 | Female | Normal | Normal | No inflammatory change | |
4 | Headache | Bechterew’s disease | 23 | 36 | Female | Fasciculations right M. vastus med | Normal | No inflammatory change | |
5 | Headache | Migraine | 55 | 49 | Female | Normal | Normal | No inflammatory change | |
6 | Headache | None | 21 | 51 | Female | Normal | n.a | No inflammatory change | |
Mild COVID-19 | 7 | Encephalopathy | Chronic heart disease, CAD, hyper-cholesterinemia, asthma | 60 | 64 | Male | Delirium, reduced vigilance, attention deficit, confusion, agitation | Normal | No inflammatory change |
8 | Impaired gait | Hyperthyreosis, reflux | 0 | 64 | Male | Sensory ataxia | Microangio-pathy | No inflammatory change | |
9 | Encephalopathy | Pneumonia, carotid stenosis | 2.5 | 74 | Female | Somnolence, increased muscle tone | Normal | No inflammatory change | |
10 | Dyspnea | Hypothyreosis, hypertension | 1 | 47 | Female | Normal | n.a | n.a | |
11 | Dyspnea | AV block °I | 10 | 60 | Male | Normal | n.a | n.a | |
12 | Cough | Diabetes type II, nephropathy, hypertension, dementia | 3 | 86 | Female | Normal | n.a | n.a | |
13 | Dyspnea | None | 1 | 42 | Female | Normal | n.a | n.a | |
14 | Dyspnea | COPD, CAD, renal insufficiency | 3 | 63 | Female | n.a | n.a | n.a | |
15 | Cold symptoms | Liver transplant, hepatitis C, renal insufficiency, osteoporosis, Diabetes type II | 0 | 51 | Male | Normal | n.a | n.a | |
16 | Fever | Agammaglobuliemia | 1 | 29 | Male | Normal | n.a | n.a | |
17 | Perineuritis n. optici | None | 4 | 33 | Male | Reduced vision | Perineuritis nervi optici | No inflammatory change | |
18 | Impaired vision | Allergic asthma | 62 | 42 | Female | Normal | Normal | No inflammatory change | |
19 | Impaired gait | None | 65 | 75 | Female | Sensory ataxia | n.a | n.a | |
20 | PNP | Hypertension | 17 | 52 | Female | Sensory ataxia | n.a | n.a | |
21 | Impaired gait | Asthma, cutaneous t-cell lymphoma, acantholytic dermatosis | 2 | 60 | Male | Sensory ataxia | n.a | n.a | |
22 | Cold symptoms | None | 2 | 31 | Female | n.a | n.a | n.a | |
23 | Cold symptoms | COPD | 2.5 | 65 | Male | Normal | n.a | n.a | |
Severe COVID-19 | 24 | Cold symptoms | Prostate cancer | 1 | 65 | Male | Normal | n.a | n.a |
25 | Dyspnea | Stroke, atrial fibrillation, hypertension, | 1 | 84 | Female | Different focal neurological deficits | n.a | n.a | |
26 | Syncope | Aortic aneurysm, sleep apnea, aortic valve replacement, hypercholesterolemia | 1 | 53 | Male | Horner syndrome right side, sensory deficit left lower arm | n.a | n.a | |
27 | Dyspnea | Renal insufficiency, CAD, peripheral artery disease, atrial fibrillation, prostate cancer, hyperlipidemia, diabetes type II | 1 | 84 | Male | Reduced vigilance | n.a | n.a | |
28 | Dyspnea | Autoimmune hepatitis, hypothyreosis, liver fibrosis, esophageal varices | 0 | 54 | Female | normal | n.a | n.a | |
29 | Cold symptoms | CAD, hypertension, diabetes type II | 1 | 82 | Female | General weakness | n.a | n.a | |
30 | Dyspnea | Cardiomoypathy, CLL, hypercholesteremia, cardiomyopathy, mitral regurgitation °I | 2 | 82 | Female | Normal | n.a | n.a | |
31 | Dyspnea | Perimyocarditis, atrial fibrillation, critical illness myopathy | 64 | 68 | Female | Hypesthesia | n.a | n.a | |
32 | Dyspnea | Autoimmune hepatitis, Hashimoto Thyroiditis, hypertension, COPD, critical illness myopathy | 4 | 64 | Female | Sensory ataxia | n.a | n.a | |
33 | Cold symptoms | Hypertension, diabetes type II, restless legs syndrome, hypothyreosis | 3 | 76 | Female | n.a | n.a | n.a | |
34 | Dyspnea | Heart Failure, atrial fibrillation, hypertension, Diabetes mellitus II, CAD, hyperlipidemia | 4 | 77 | Female | External oculo-motor nerve palsy | n.a | No inflammatory change | |
COVID-19-negative controls | 35 | PPA | Gonarthrosis, hypercholesterinemia, hyperhomocysteinemia, glaucoma | 0 | 62 | Female | Cognitive deficits | Temporal lobe atrophy | No inflammatory change |
36 | Idiopathic intracranial hypertension | Asthma, thyroid carcinoma, sarcoidosis | 0 | 42 | Female | Normal | n.a | No inflammatory change | |
37 | Idiopathic intracranial hypertension | None | 0 | 32 | Male | Normal | n.a | n.a | |
38 | Headache | None | 0 | 39 | Male | Normal | n.a | n.a | |
39 | None | None | 0 | 27 | Female | Normal | n.a | n.a | |
40 | None | Diabetes mellitus II | 0 | 34 | Female | Normal | n.a | n.a | |
41 | Polyneuropathy | obstructive sleep apnea, hypogonadotropic hypogonadism | 0 | 57 | Male | Sensory ataxia | n.a | n.a | |
42 | Seizure | Structural epilepsy, asthma, Spondylose deformans, hypertension | 0 | 73 | Male | Reduced vigilance | n.a | n.a | |
43 | n.a | n.a | n.a | n.a | n.a | n.a | n.a | n.a | |
44 | n.a | n.a | n.a | n.a | n.a | n.a | n.a | n.a | |
45 | n.a | n.a | n.a | n.a | n.a | n.a | n.a | n.a | |
46 | n.a | n.a | n.a | n.a | n.a | n.a | n.a | n.a | |
47 | n.a | Hemophilia A, liver transplant, polyneuropathy, renal insufficiency | 0 | 68 | Male | n.a | n.a | n.a | |
48 | Cold symptoms | None | 0 | 37 | Female | Normal | n.a | n.a |