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Table 1 Comparison of direct transfer to CSC vs secondary emergency transfer in a telestroke setting in suspected AIS due to LVO

From: Telestroke networks for area-wide access to endovascular stroke treatment

Reference [No.]

Barlinn et al. [29]

Kaminsky et al. [31]

Moustafa et al. [28]

Number of patients

151

207

163

Vascular screening criteria

Anterior circulation, LVO

Anterior and vertebrobasilar, suspected LVO

Anterior circulation, LVO

Center type

CSC/MS

Spoke/DS

CSC/MS

Spoke/DS

CSC/MS

Spoke/DS

Proportion of patients [%]

68.2

31.8

63.8

36.2

55.8

44.2

Age [years]

70 (62–75)*

66 (59–73)*

72.8 (13.5)**

74.5 (15.2)**

76 (65–83)*

76 (66–80)*

NIHSS at admission

15 (11–21)*

15 (12–18)*

16 (10–20) *

17 (13.5–20)*

16 (12–20)*

17 (14–20)*

IVT [%]

46.6

70.8

53.8

81.3

59.3

51.4

EVT [%]

100

100

49.2

26.7

100

100

Onset to groin [min]

225 (175–293)*

319 (270–384)*

200.5 (71.5)**

303.0 (44.3)**

180 (132–220)*

295 (248–340)*

Favorable outcome [mRS 0–2) [%]

Discharge 13.7

Discharge 18.8

3 months 35.1

3 months 32.1

3 months 28.6

3 months 25.4

ICH [%]

11.7 (symptomatic)

4.2 (symptomatic)

43.3 (all ICH)

25.4 (all ICH)

1.1 (symptomatic)

2.8 (symptomatic)

Mortality [%]

Discharge 22.6

Discharge 8.3

3 months 25.2

3 months 37.2

3 months 33.0

3 months 26.8

  1. AIS Acute ischemic stroke; CSC Comprehensive stroke center; DS Drip-and-ship; EVT Endovascular treatment; ICH Intracerebral hemorrhage; IVT Intravenous thrombolysis; LVO Large vessel occlusion; mRS Modified rankin scale; MS Mothership; NIHSS National Institutes of Health Stroke Scale; Spoke telemedical site with stroke care
  2. *Median (IQR); **mean (SD); bold statistically significant (p < 0.05)