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  1. Cervical dystonia (CD) is characterized by involuntary contractions of the cervical muscles. Data on long-term effectiveness of deep brain stimulation (DBS) are rare. The aim of this study was to evaluate the ...

    Authors: Clemens Jacksch, Kirsten E. Zeuner, Ann-Kristin Helmers, Karsten Witt, Günther Deuschl and Steffen Paschen
    Citation: Neurological Research and Practice 2022 4:48
  2. Several non-motor symptoms are present in Parkinson's disease (PD), including increasing prevalence rates of cognitive impairment during disease progression. Due to its multifaceted nature, PD management invol...

    Authors: Jennifer Michels, Cornelius J. Werner, Beate Schumann-Werner, Jörg B. Schulz, Ana S. Costa and Kathrin Reetz
    Citation: Neurological Research and Practice 2022 4:47
  3. This study aims to characterize the impact of apraxia and visuospatial neglect on stroke patients’ cognitive and functional outcomes during early rehabilitation. Prior work implies an unfavorable effect of vis...

    Authors: S. Latarnik, J. Stahl, S. Vossel, C. Grefkes, G. R. Fink and P. H. Weiss
    Citation: Neurological Research and Practice 2022 4:46
  4. To mitigate the potential consequences of the coronavirus disease 2019 (COVID-19) pandemic on public life, the German Federal Government and Ministry of Health enacted a strict lockdown protocol on March 16, 2...

    Authors: Kimberly Körbel, Felix Rosenow, Margarita Maltseva, Heiko Müller, Juliane Schulz, Panagiota-Eleni Tsalouchidou, Lisa Langenbruch, Stjepana Kovac, Katja Menzler, Mario Hamacher, Felix von Podewils, Laurent M. Willems, Catrin Mann and Adam Strzelczyk
    Citation: Neurological Research and Practice 2022 4:44
  5. Autoimmune-mediated neural inflammation can affect both the central and the peripheral nervous system. Recently, antibodies against the peripheral membrane protein flotillin have been described in patients wit...

    Authors: Tobias A. Wagner-Altendorf, Klaus-Peter Wandinger, Robert Markewitz, Anna Antufjew, Tobias Boppel and Thomas F. Münte
    Citation: Neurological Research and Practice 2022 4:43
  6. Oral anticoagulation (OAC) is the mainstay of secondary prevention in ischemic stroke patients with atrial fibrillation (AF). However, in AF patients with large vessel occlusion stroke treated by endovascular ...

    Authors: Johannes M. Weller, Franziska Dorn, Julius N. Meissner, Sebastian Stösser, Niklas M. Beckonert, Julia Nordsiek, Christine Kindler, Christoph Riegler, Fee Keil, Gabor C. Petzold and Felix J. Bode
    Citation: Neurological Research and Practice 2022 4:42
  7. Brain tumor related epilepsy (BTRE) is a common complication of cerebral tumors and its incidence is highly dependent on the type of tumor, ranging from 10–15% in brain metastases to > 80% in low grade gliomas...

    Authors: Sabine Seidel, Tim Wehner, Dorothea Miller, Jörg Wellmer, Uwe Schlegel and Wenke Grönheit
    Citation: Neurological Research and Practice 2022 4:45
  8. With the optimization of medical care structures and the rapid progress in the development of new therapeutic methods, an increase in life expectancy is observed in patients with neuromuscular diseases. This l...

    Authors: Michael Fleischer, Bayram Coskun, Benjamin Stolte, Adela Della-Marina, Heike Kölbel, Hildegard Lax, Michael Nonnemacher, Christoph Kleinschnitz, Ulrike Schara-Schmidt and Tim Hagenacker
    Citation: Neurological Research and Practice 2022 4:41
  9. Chronic headache due to the overuse of medication for the treatment of migraine attacks has a prevalence of 0.5–2.0%. This guideline provides guidance for the management of medication overuse (MO) and medicati...

    Authors: Hans-Christoph Diener, Peter Kropp, Thomas Dresler, Stefan Evers, Stefanie Förderreuther, Charly Gaul, Dagny Holle-Lee, Arne May, Uwe Niederberger, Sabrina Moll, Christoph Schankin and Christian Lampl
    Citation: Neurological Research and Practice 2022 4:37
  10. Hypoglycemia in patients with diabetes mellitus, particularly type 1 can mimic acute ischemic stroke by causing focal neurological deficits. In acute ischemic stroke, the interpretation of emergency imaging in...

    Authors: Jennifer Sartor-Pfeiffer, Mirjam Lingel, Maria-Ioanna Stefanou, Tobias Lindig, Benjamin Bender, Sven Poli, Ulf Ziemann, Andreas Fritsche, Katharina Feil and Annerose Mengel
    Citation: Neurological Research and Practice 2022 4:36
  11. Super-refractory status epilepticus (SRSE) represents the culmination of refractory status epilepticus (RSE) and carries a significant risk of poor neurological outcome and high mortality. RSE is not defined p...

    Authors: Michael P Malter and Janina Neuneier
    Citation: Neurological Research and Practice 2022 4:35
  12. Adenylyl cyclase 5 (ADCY5) related dyskinesia is a rare disorder characterized by early-onset paroxysmal choreoathetosis, dystonia, myoclonus, or a combination of the above, which primarily involved the limbs,...

    Authors: Shih-Ying Chen, Chen-Jui Ho, Yan-Ting Lu, Chih-Hsiang Lin and Meng-Han Tsai
    Citation: Neurological Research and Practice 2022 4:39
  13. In order to inspire and attract young people to Neurology, we must offer high-quality and attractive teaching! To improve neurological education at our Medical School (Technical University of Munich), we conve...

    Authors: Katharina Mosene, Henrik Heitmann, Dennis Pötter and Friederike Schmidt-Graf
    Citation: Neurological Research and Practice 2022 4:31
  14. Levamisole is a common adulterant of cocaine and has been associated with reversible leukoencephalopathy in cocaine users. We report a case of two episodes with severe neurological symptoms and multifocal whit...

    Authors: Nadine Tollens, Philip Post, Michael Martins Dos Santos, Pascal Niggemann, Melanie Warken and Joachim Wolf
    Citation: Neurological Research and Practice 2022 4:38
  15. Central retinal artery occlusion (CRAO) is a neuro-ophthalmological emergency whose optimal management is still under debate and due to the absence of definite guidelines, practice is expected to vary. We aime...

    Authors: Carolin Hoyer, Simon Winzer, Egbert Matthé, Ida Heinle, Vesile Sandikci, Darius Nabavi, Michael Platten, Volker Puetz and Kristina Szabo
    Citation: Neurological Research and Practice 2022 4:30
  16. Subacute cerebellar ataxia combined with cerebrospinal fluid (CSF) pleocytosis is the result of an immune response that can occur due to viral infections, paraneoplastic diseases or autoimmune-mediated mechani...

    Authors: Christof Klötzsch, Matthias Böhmert, Ruxandra Hermann, Bianca Teegen, Kristin Rentzsch and Andreas Till
    Citation: Neurological Research and Practice 2022 4:29
  17. The ongoing expansion of the cosmetic armamentarium of facial rejuvenation fails to uncover the inherent risks of cosmetic interventions. Informed consent to all risks of cosmetic filler injections and potenti...

    Authors: Alexandra Lucaciu, Patrick Felix Samp, Elke Hattingen, Roxane-Isabelle Kestner, Petra Davidova, Thomas Kohnen, Jasmin Rudolph, Andreas Dietz, Helmuth Steinmetz and Adam Strzelczyk
    Citation: Neurological Research and Practice 2022 4:40
  18. Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to COVID-19 (COrona VIrus Disease-2019). SARS-CoV-2 acute infection may be associated with an increased incidence of neurol...

    Authors: Christiana Franke, Peter Berlit and Harald Prüss
    Citation: Neurological Research and Practice 2022 4:28
  19. The individualized clinical and public health management of the COVID-19 pandemic have changed over time, including care of people with PD. The objective was to investigate whether in-hospital COVID-19 outcome...

    Authors: Raphael Scherbaum, Dirk Bartig, Daniel Richter, Eun Hae Kwon, Siegfried Muhlack, Ralf Gold, Christos Krogias and Lars Tönges
    Citation: Neurological Research and Practice 2022 4:27
  20. As part of a larger project commissioned by the German Neurological Society (DGN), this paper focuses on the DGN’s German and Austrian honorary members. In particular, the question of whether former membership...

    Authors: Michael Martin, Heiner Fangerau and Axel Karenberg
    Citation: Neurological Research and Practice 2022 4:26
  21. External ventricular drains (EVD) are commonly used in aneurysmal subarachnoid hemorrhage (aSAH) patients and can be life-saving by diverting cerebrospinal fluid. However, the overall relationship between EVD ...

    Authors: Sarah E. Nelson, Jose I. Suarez, Alexander Sigmon, Jun Hua, Casey Weiner, Haris I. Sair and Robert D. Stevens
    Citation: Neurological Research and Practice 2022 4:25
  22. A 71-year-old male patient was diagnosed with LGI1 encephalopathy 4 weeks following a first ChAdOx1 nCov-19 vaccination. Extensive work-up including analysis of CSF and PET examination did not reveal a tangibl...

    Authors: Tamara Garibashvili and Josef Georg Heckmann
    Citation: Neurological Research and Practice 2022 4:24
  23. Extracranial artery dissection involving either internal carotid artery or vertebral artery is a major cause of stroke in adults under 50 years of age. There is no conclusive evidence whether antiplatelets or ...

    Authors: Ei Zune The, Ne Naing Lin, Ching Jocelyn Chan, Jason Cher Wei Loon, Benjamin Yong-Qiang Tan, Chee Seong Raymond Seet, Hock Luen Teoh, Joy Vijayan and Leong Litt Leonard Yeo
    Citation: Neurological Research and Practice 2022 4:23
  24. In Dravet syndrome (DS), a rare epileptic and developmental encephalopathy, the effectiveness of a new treatment is predominantly measured in terms of seizure frequency. However, this may not fully capture the...

    Authors: Adam Strzelczyk, Gerhard Kurlemann, Thomas Bast, Ulrich Bettendorf, Gerhard Kluger, Thomas Mayer, Bernd A. Neubauer, Tilman Polster, Sarah von Spiczak, Regina Trollmann, Markus Wolff, Toby Toward, Jens Gruenert, Eddie Gibson, Clive Pritchard, Joe Carroll…
    Citation: Neurological Research and Practice 2022 4:22
  25. Isocitrate dehydrogenase (IDH) mutations are disease-defining mutations in IDH-mutant astrocytomas and IDH-mutant and 1p/19q-codeleted oligodendrogliomas. In more than 80% of these tumors, point mutations in I...

    Authors: Lukas Bunse, Anne-Kathleen Rupp, Isabel Poschke, Theresa Bunse, Katharina Lindner, Antje Wick, Jens Blobner, Martin Misch, Ghazaleh Tabatabai, Martin Glas, Oliver Schnell, Jens Gempt, Monika Denk, Guido Reifenberger, Martin Bendszus, Patrick Wuchter…
    Citation: Neurological Research and Practice 2022 4:20
  26. Optimal treatment of intracranial stenoses in varicella zoster virus (VZV)-associated vasculitis is unknown. This study aims to evaluate the merits and potential pitfalls of a specific therapeutic strategy, in...

    Authors: Markus Kraemer, Daniel Strunk, Jana Becker, Roland Veltkamp and Peter Berlit
    Citation: Neurological Research and Practice 2022 4:18
  27. Residents play an important role in the clinical training of medical students, spending up to 25% of their daily work teaching. In the US medical curriculum didactic courses for residents already exist and the...

    Authors: Anne-Sophie Biesalski, Lars Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, Franziska Maria Ippen and Friederike Schmidt-Graf
    Citation: Neurological Research and Practice 2022 4:17
  28. The use of direct oral anticoagulants (DOAC) has increased sharply and DOAC are the oral anticoagulant therapy (OAT) of choice for the majority of patients with newly-diagnosed atrial fibrillation. Intracrania...

    Authors: Waltraud Pfeilschifter, Edelgard Lindhoff-Last, Ali Alhashim, Barbara Zydek, Simone Lindau, Stavros Konstantinides, Oliver Grottke, Ulrike Nowak-Göttl, Christian von Heymann, Ingvild Birschmann, Jan Beyer-Westendorf, Patrick Meybohm, Andreas Greinacher and Eva Herrmann
    Citation: Neurological Research and Practice 2022 4:16
  29. Anti-NMDA-receptor (anti-NMDAR) encephalitis is often associated with ovarian teratoma (OT). The best management of anti-NMDAR encephalitis patients with normal imaging studies (pelvic ultrasound/MRI) but clin...

    Authors: Christoph Cirkel, Anna Cirkel, Georg Royl, Alex Frydrychowicz, Lars Tharun, Steffen Deichmann, Achim Rody, Thomas F. Münte and Björn Machner
    Citation: Neurological Research and Practice 2022 4:15
  30. The WHO estimates that each year 5 million people are left permanently disabled after stroke. Adjuvant treatments to promote the effects of rehabilitation are urgently needed. Cortical excitability and neuropl...

    Authors:
    Citation: Neurological Research and Practice 2022 4:14
  31. Early prehospital stroke identification is crucial for goal directed hospital admission especially in rural areas. However, clinical prehospital stroke scales are designed to identify any stroke but cannot suf...

    Authors: Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S. Liebeskind and Felix Schlachetzki
    Citation: Neurological Research and Practice 2022 4:13
  32. Sickle cell disease (SCD) is one of the most prevalent monogenetic diseases worldwide and one of the most serious complications is stroke. Transcranial Doppler (TCD) demonstrated to be highly predictive for an...

    Authors: Sylvia Thurn, Katharina Kleinschmidt, Irena Kovacic, Christina Wendl, Ralf A. Linker, Selim Corbacioglu and Felix Schlachetzki
    Citation: Neurological Research and Practice 2022 4:12
  33. In this letter we raise several concerns regarding the interesting article by Walter and Krämer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine...

    Authors: Josef Finsterer, Fulvio A. Scorza, Carla A. Scorza and Ana C. Fiorini
    Citation: Neurological Research and Practice 2022 4:10
  34. Parkinson’s disease (PD) is a progressive, neurodegenerative disorder. In the advanced stages it can result in severe disability despite optimal treatment. Data suggests heterogeneous classification of PD stag...

    Authors: David J. Pedrosa, Florin Gandor, Wolfgang H. Jost, Carolin Arlt, Koray Onuk and Lars Timmermann
    Citation: Neurological Research and Practice 2022 4:9
  35. Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by a prolonged, but self-limiting segmental cerebral vasoconstriction. Neurological outcomes vary, but can be severe. The clinical hallmark...

    Authors: Daniel Strunk, Roland Veltkamp, Sven G. Meuth, René Chapot and Markus Kraemer
    Citation: Neurological Research and Practice 2022 4:8
  36. Based on demographical trends and the expected worldwide increase in the number of individuals with atrial fibrillation, the rate of patients who are on oral anticoagulation therapy for secondary prevention of...

    Authors: Pawel Kermer, Peter D. Schellinger, Peter A. Ringleb and Martin Köhrmann
    Citation: Neurological Research and Practice 2022 4:7
  37. This correspondence comments on a published article presenting a case of rhombencephalitis following SARS-CoV-2-vaccination with the mRNA vaccine BNT162b2 (Pfizer/BioNTech). We also present the case of a 47-ye...

    Authors: Maria Ioanna Stefanou, Eleni Karachaliou, Maria Chondrogianni, Christos Moschovos, Eleni Bakola, Aikaterini Foska, Konstantinos Melanis, Elisabeth Andreadou, Konstantinos Voumvourakis, Matilda Papathanasiou, Eleni Boutati and Georgios Tsivgoulis
    Citation: Neurological Research and Practice 2022 4:6
  38. By whole-exome sequencing, we found the heterozygous POLG variant c.3542G>A; p.Ser1181Asn in a family of four affected individuals, presenting with a mixed neuro-myopathic phenotype. The variant is located within...

    Authors: Maike F. Dohrn, Corina Heller, Diana Zengeler, Carolin D. Obermaier, Saskia Biskup, Joachim Weis, Stefan Nikolin, Kristl G. Claeys, Ulrike Schöne, Danique Beijer, Natalie Winter, Pascal Achenbach, Burkhard Gess, Jörg B. Schulz and Lejla Mulahasanovic
    Citation: Neurological Research and Practice 2022 4:5
  39. Nearly one in three unconscious cardiac arrest survivors experience post-anoxic status epilepticus (PASE). Historically, PASE has been deemed untreatable resulting in its exclusion from status epilepticus clin...

    Authors: Carolina B. Maciel, Fernanda J. P. Teixeira, Katie J. Dickinson, Jessica C. Spana, Lisa H. Merck, Alejandro A. Rabinstein, Robert Sergott, Guogen Shan, Guanhong Miao, Charles A. Peloquin, Katharina M. Busl and Lawrence J. Hirsch
    Citation: Neurological Research and Practice 2022 4:4
  40. The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, en...

    Authors: Deborah K. Erhart, Vera Bracknies, Susanne Lutz-Schuhbauer, Sonja Wigand and Hayrettin Tumani
    Citation: Neurological Research and Practice 2022 4:3
  41. Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblasti...

    Authors: Nora Möhn, Viktoria Bonda, Lea Grote-Levi, Victoria Panagiota, Tabea Fröhlich, Christian Schultze-Florey, Mike P. Wattjes, Gernot Beutel, Matthias Eder, Sascha David, Sonja Körner, Günter Höglinger, Martin Stangel, Arnold Ganser, Christian Koenecke and Thomas Skripuletz
    Citation: Neurological Research and Practice 2022 4:1
  42. Major efforts have been made in the last decade to develop and improve therapies for proximal spinal muscular atrophy (SMA). The introduction of Nusinersen/Spinrazaâ„¢ as an antisense oligonucleotide therapy, On...

    Authors: Sibylle Jablonka, Luisa Hennlein and Michael Sendtner
    Citation: Neurological Research and Practice 2022 4:2
  43. Impaired motor functions after stroke are common and negatively affect patients' activities of daily living and quality of life. In particular, hand motor function is essential for daily activities, but often ...

    Authors: Thies Ingwersen, Silke Wolf, Gunnar Birke, Eckhard Schlemm, Christian Bartling, Gabriele Bender, Alfons Meyer, Achim Nolte, Katharina Ottes, Oliver Pade, Martin Peller, Jochen Steinmetz, Christian Gerloff and Götz Thomalla
    Citation: Neurological Research and Practice 2021 3:66
  44. Deep brain stimulation of the internal globus pallidus is an effective treatment for dystonia. However, there is a large variability in clinical outcome with up to 25% non-responders even in highly selected pr...

    Authors: Florian Lange, Jonas Roothans, Tim Wichmann, Götz Gelbrich, Christoph Röser, Jens Volkmann and Martin Reich
    Citation: Neurological Research and Practice 2021 3:65

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