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Table 2 A brief list of actively recruiting or completed large clinical trials using RApid processing of PerfusIon and Diffusion [RAPID] software (iSchemaView, Menlo Park, USA) for assessment of CT- and MRI- perfusion images

From: Computer-aided imaging analysis in acute ischemic stroke – background and clinical applications

Trial Name RAPID Number of Patients Status Reference
DWI or CTP Assessment with Clinical Mismatch
in the Triage of Wake-Up and Late Presenting
Strokes Undergoing Neurointervention with Trevo (DAWN)
imaging selection for 100% of patients 206 Completed [72]
The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study imaging selection for 100% of patients 74 Completed [61]
The diffusion and perfusion imaging evaluation for understanding stroke evolution 3(DEFUSE 3) study imaging selection for 100% of patients 182 Completed [38]
Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND) imaging selection for 100% of patients 225 Completed [73]
Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial (EXTEND-IA) imaging selection for 100% of patients 70 Completed [74]
FRench Acute Cerebral Multimodal Imaging to Select Patient for MEchanical Thrombectomy (FRAME) imaging selection for 100% of patients Estimated Enrollment:
220 participants
Enrolling ClinicalTrials.gov Identifier: NCT03045146
Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial imaging selection for 100% of patients 196 Completed [75]