Table 2 A brief list of actively recruiting or completed large clinical trials using RApid processing of PerfusIon and Diffusion [RAPID] software (iSchemaView, Menlo Park, USA) for assessment of CT- and MRI- perfusion images
From: Computer-aided imaging analysis in acute ischemic stroke – background and clinical applications
Trial Name | RAPID | Number of Patients | Status | Reference |
|---|---|---|---|---|
DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo (DAWN) | imaging selection for 100% of patients | 206 | Completed | [72] |
The diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study | imaging selection for 100% of patients | 74 | Completed | [61] |
The diffusion and perfusion imaging evaluation for understanding stroke evolution 3(DEFUSE 3) study | imaging selection for 100% of patients | 182 | Completed | [38] |
Extending the Time for Thrombolysis in Emergency Neurological Deficits (International) (EXTEND) | imaging selection for 100% of patients | 225 | Completed | [73] |
Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial (EXTEND-IA) | imaging selection for 100% of patients | 70 | Completed | [74] |
FRench Acute Cerebral Multimodal Imaging to Select Patient for MEchanical Thrombectomy (FRAME) | imaging selection for 100% of patients | Estimated Enrollment: 220 participants | Enrolling | ClinicalTrials.gov Identifier: NCT03045146 |
Solitaire™ With the Intention For Thrombectomy as PRIMary Endovascular Treatment (SWIFT PRIME) Trial | imaging selection for 100% of patients | 196 | Completed | [75] |