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  1. Sphingosin-1-phosphate (S1P) plays a crucial role as a signaling molecule in the immune system and the vasculature. Previous studies suggested a role as a vasoconstrictor of cerebral arteries via the S1P3-Rece...

    Authors: Anika Männer, Dominique Thomas, Marlies Wagner, Jürgen Konczalla, Helmuth Steinmetz, Robert Brunkhorst and Waltraud Pfeilschifter

    Citation: Neurological Research and Practice 2020 2:49

    Content type: Research article

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  2. The Coronavirus Disease 2019 (COVID-19) pandemic may have altered emergency workflows established to optimize the outcome of patients with large-vessel occlusion (LVO) stroke.

    Authors: Steffen Tiedt, Felix J. Bode, Timo Uphaus, Anna Alegiani, Klaus Gröschel and Gabor C. Petzold

    Citation: Neurological Research and Practice 2020 2:44

    Content type: Research article

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  3. One quarter to one third of patients eligible for systemic thrombolysis are on antiplatelet therapy at presentation. In this study, we aimed to assess the safety and efficacy of intravenous thrombolysis in str...

    Authors: Benedikt M. Frey, Florent Boutitie, Bastian Cheng, Tae-Hee Cho, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ian Ford, Ivana Galinovic, Alina Königsberg, Josep Puig, Pascal Roy, Anke Wouters, Tim Magnus, Vincent Thijs…

    Citation: Neurological Research and Practice 2020 2:40

    Content type: Research article

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  4. Comparing health care parameters of acute ischemic stroke (AIS) patients with and without concurrent coronavirus disease 2019 (Covid-19, SARS-CoV-2 infection), may be helpful in terms of optimizing clinical an...

    Authors: Daniel Richter, Christos Krogias, Jens Eyding, Dirk Bartig, Armin Grau and Ralph Weber

    Citation: Neurological Research and Practice 2020 2:48

    Content type: Letter to the editor

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  5. In view of the importance of neurosyphilis and the difficulties encountered in diagnosing it, the S1 guideline “Neurosyphilis” has been published by the German Society for Neurology (DGN) in accordance with th...

    Authors: Matthias Klein, Klemens Angstwurm, Stefan Esser, Kathrin Hahn, Matthias Maschke, Simone Scheithauer, Helmut Schoefer, Matthias Sturzenegger, Brigitte Wildemann and Jörg Weber

    Citation: Neurological Research and Practice 2020 2:33

    Content type: Guidelines

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  6. Investigating clinical characteristics of patients presenting with cerebrovascular events during the pandemic may provide valuable insight into further understanding the phenomenon of decreased stroke admissio...

    Authors: Carolin Hoyer, Lenja Weber, Vesile Sandikci, Anne Ebert, Michael Platten and Kristina Szabo

    Citation: Neurological Research and Practice 2020 2:47

    Content type: Letter to the editor

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  7. At present, “severe acute respiratory syndrome new coronavirus” (SARS-CoV-2) affects the whole world and has led to a pandemia with almost 2.000.000 infected patients in the mid of April 2020 (WHO). Thus, heal...

    Authors: Christian Urbanek, Jana Kötteritzsch, Wolfgang Zink and Armin J. Grau

    Citation: Neurological Research and Practice 2020 2:32

    Content type: Research article

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  8. The presence of motor signs and symptoms in Parkinson’s disease (PD) is the result of a long-lasting prodromal phase with an advancing neurodegenerative process. The identification of PD patients in an early p...

    Authors: Jannik Prasuhn, Marcus Heldmann, Thomas F. Münte and Norbert Brüggemann

    Citation: Neurological Research and Practice 2020 2:46

    Content type: Research article

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  9. “Printed by Parkinson’s” is an innovative project with the main aim to raise awareness for the many aspects of Parkinson’s disease and their implication for everyday life. In a cooperation of Innocean Worldwid...

    Authors: Lucia K. Feldmann and Andrea A. Kühn

    Citation: Neurological Research and Practice 2020 2:37

    Content type: Letter to the editor

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  10. The advent of therapeutic strategies designed to modify the disease course in Parkinson’s disease has raised great expectations in the currently conducted clinical trials. However, we see ethical challenges in...

    Authors: D. Berg, K. Eggert, B. Haslinger, J. Kassubek, B. Mollenhauer, K. Reetz, A. Rogge, E. Schaeffer, L. Tönges and K. E. Zeuner

    Citation: Neurological Research and Practice 2020 2:31

    Content type: Position statement

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  11. Recently different subtypes of myasthenia gravis (MG) have been described. They differ for clinical features and pathogenesis but the prognosis and response to treatment is less clear. The aim of the study was...

    Authors: Francesca Pasqualin, Silvia V. Guidoni, Mario Ermani, Elena Pegoraro and Domenico M. Bonifati

    Citation: Neurological Research and Practice 2020 2:45

    Content type: Research article

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  12. Dementia in Parkinson’s disease (PDD) is a common non-motor symptom of advanced disease, associated with pronounced neocortical cholinergic deficits due to neurodegeneration of the nucleus basalis of Meynert (...

    Authors: Christine Daniels, Frank Steigerwald, Philipp Capetian, Cordula Matthies, Uwe Malzahn, Peter U. Heuschmann and Jens Volkmann

    Citation: Neurological Research and Practice 2020 2:41

    Content type: Clinical trial protocol

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  13. Nowadays B-cell depletion via anti-CD20 antibodies is commonly applied in the treatment of multiple sclerosis (MS). Yet, not much is known about infection risks associated with long-term B-cell depletion in th...

    Authors: Carolin Schwake and Ralf Gold

    Citation: Neurological Research and Practice 2020 2:30

    Content type: Letter to the editor

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  14. Lumbar punctures are performed in different medical settings and are a key procedure in the diagnosis of several neurological conditions. Complications are rare and generally self-limiting. There are no report...

    Authors: Aleksander Fjeld Haugstvedt, Inger Birgitte Havsteen and Hanne Christensen

    Citation: Neurological Research and Practice 2020 2:36

    Content type: Letter to the editor

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  15. After the end of Nazi terrorism with many crimes against neuropsychiatric and disabled people, from 1950 on detection and treatment of these diseases in children and adolescents grew continuously: in the 50s a...

    Authors: Hans Michael Strassburg

    Citation: Neurological Research and Practice 2020 2:28

    Content type: Review

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  16. Postural control is a very important function in everyday life. However, assessing postural control with commonly used measurement instruments (MIs) is limited due to deficits in their psychometric properties....

    Authors: Elena Cramer, Franziska Weber, Gilian Faro, Michael Klein, Dennis Willeke, Thomas Hering and Dörte Zietz

    Citation: Neurological Research and Practice 2020 2:27

    Content type: Research article

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  17. Traditionally, cerebellar disorders including ataxias have been associated with deficits in motor control and motor learning. Since the 1980’s growing evidence has emerged that cerebellar diseases also impede ...

    Authors: Andreas Thieme, Sandra Roeske, Jennifer Faber, Patricia Sulzer, Martina Minnerop, Saskia Elben, Heike Jacobi, Kathrin Reetz, Imis Dogan, Miriam Barkhoff, Juergen Konczak, Elke Wondzinski, Mario Siebler, Oliver Mueller, Ulrich Sure, Jeremy D. Schmahmann…

    Citation: Neurological Research and Practice 2020 2:39

    Content type: Clinical trial protocol

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  18. Cerebellar transcranial direct current stimulation (tDCS) is widely considered as a promising non-invasive tool to foster motor performance and learning in health and disease. The results of previous studies, ...

    Authors: M. Rauscher, F. Yavari, G. Batsikadze, N. Ludolph, W. Ilg, M. A. Nitsche, D. Timmann and K. M. Steiner

    Citation: Neurological Research and Practice 2020 2:38

    Content type: Research article

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  19. It is still unclear, which physiotherapeutic approaches are most effective in stroke recovery. Vojta therapy is a type of physiotherapy that was originally developed for children and adolescents with cerebral ...

    Authors: Corina Epple, Barbara Maurer-Burkhard, Mari-Carmen Lichti and Thorsten Steiner

    Citation: Neurological Research and Practice 2020 2:23

    Content type: Research article

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  20. The anatomical distribution of acute lacunar infarcts has mainly been studied for supratentorial lesions. In addition, little is known about the association with distinct stroke symptoms, not summarized as cla...

    Authors: Ewgenia Barow, Hans Pinnschmidt, Florent Boutitie, Alina Königsberg, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Vincent Thijs, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla…

    Citation: Neurological Research and Practice 2020 2:21

    Content type: Research article

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  21. The targeted use of endovascular therapy (EVT), with or without intravenous thrombolysis (IVT) in acute large cerebral vessel occlusion stroke (LVOS) has been proven to be superior compared to IVT alone. Despi...

    Authors: Philipp Ettelt, Ilko L. Maier, Marlena Schnieder, Mathias Bähr, Daniel Behme, Marios-Nikos Psychogios and Jan Liman

    Citation: Neurological Research and Practice 2020 2:29

    Content type: Research article

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  22. Peripheral neuropathy represents a spectrum of diseases with different etiologies. The most common causes are diabetes, exposure to toxic substances including alcohol and chemotherapeutics, immune-mediated con...

    Authors: Helmar C. Lehmann, Gilbert Wunderlich, Gereon R. Fink and Claudia Sommer

    Citation: Neurological Research and Practice 2020 2:20

    Content type: Standard operating procedure

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  23. Since January 2020, after Chinese health authorities identified a new type of coronavirus (SARS-CoV-2), the virus has spread throughout China and consecutively throughout the whole world. The most common sympt...

    Authors: Anne Lampe, Alexander Winschel, Cornelie Lang and Thorsten Steiner

    Citation: Neurological Research and Practice 2020 2:19

    Content type: Letter to the editor

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  24. A brief survey among members of the German Neurorehabilitation Society aimed to document the hospital capacities (“beds”) for prolonged weaning from a mechanical ventilator for patients with neuro-disabilities...

    Authors: Thomas Platz, Andreas Bender, Christian Dohle, Anna Gorsler, Stefan Knecht, Joachim Liepert, Thomas Mokrusch and Michael Sailer

    Citation: Neurological Research and Practice 2020 2:18

    Content type: Letter to the editor

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  25. Stroke is a leading cause of acquired, permanent disability worldwide. Although the treatment of acute stroke has been improved considerably, the majority of patients to date are left disabled with a considera...

    Authors: Christian Grefkes and Gereon R. Fink

    Citation: Neurological Research and Practice 2020 2:17

    Content type: Review

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  26. 2019 the DGN (Deutsche Gesellschaft für Neurology) published a new guideline on the diagnosis and non-interventional therapy of neuropathic pain of any etiology excluding trigeminal neuralgia and CRPS (complex...

    Authors: Tanja Schlereth

    Citation: Neurological Research and Practice 2020 2:16

    Content type: Guidelines

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  27. The study design of PIMIDES, a trial based on patient-individualized transcranial electric neurostimulation of epileptic foci, is reported. Inclusion criteria include a predominant epileptic focus and pharmaco...

    Authors: Kristina Kravalis and Andreas Schulze-Bonhage

    Citation: Neurological Research and Practice 2020 2:15

    Content type: Clinical trial protocol

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  28. This paper aims to provide an overview of the use and assessment of qualitative research methods in the health sciences. Qualitative research can be defined as the study of the nature of phenomena and is especial...

    Authors: Loraine Busetto, Wolfgang Wick and Christoph Gumbinger

    Citation: Neurological Research and Practice 2020 2:14

    Content type: Review

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  29. Cerebral small vessel disease (CSVD) is a disorder of brain vasculature that causes various structural changes in the brain parenchyma, and is associated with various clinical symptoms such as cognitive impair...

    Authors: A. Abdelhak, A. Huss, A. Brück, U. Sebert, B. Mayer, H. P. Müller, H. Tumani, M. Otto, D. Yilmazer-Hanke, A. C. Ludolph, J. Kassubek, E. Pinkhardt and H. Neugebauer

    Citation: Neurological Research and Practice 2020 2:13

    Content type: Research article

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  30. About 6.2 million adults in Germany cannot read and write properly despite attending school for several years. They are considered to be functional illiterates (FI). Since the ability to read and write is cruc...

    Authors: Bahram Mohammadi, Thomas F. Münte, David M. Cole, Amir Sami, Melanie Boltzmann and Jascha Rüsseler

    Citation: Neurological Research and Practice 2020 2:12

    Content type: Research article

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  31. Monoclonal antibodies against the calcitonin gene-related peptide (CGRP) receptor (Erenumab) or against CGRP (Eptinezumab, Fremanezumab, Galcanezumab) are new substances for the preventive treatment of migrain...

    Authors: Hans-Christoph Diener, Stefanie Förderreuther, Charly Gaul, Florian Giese, Till Hamann, Dagny Holle-Lee, Tim P. Jürgens, Katharina Kamm, Torsten Kraya, Christian Lampl, Arne May, Uwe Reuter, Armin Scheffler and Peer Tfelt-Hansen

    Citation: Neurological Research and Practice 2020 2:11

    Content type: Guideline

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  32. Stroke and its long-term consequences pose major challenges for the lives of those affected and healthcare systems. Neurological rehabilitation therefore primarily attempts to improve function in order to incr...

    Authors: Gunnar Birke, Silke Wolf, Thies Ingwersen, Christian Bartling, Gabriele Bender, Alfons Meyer, Achim Nolte, Katharina Ottes, Oliver Pade, Martin Peller, Jochen Steinmetz, Christian Gerloff and Götz Thomalla

    Citation: Neurological Research and Practice 2020 2:10

    Content type: Clinical trial protocol

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  33. Removal of a tracheostomy tube in critically ill neurologic patients is a difficult issue, particularly due to the high incidence of oropharyngeal dysphagia. For an objective evaluation of decannulation readin...

    Authors: Tobias Warnecke, Paul Muhle, Inga Claus, Jens B. Schröder, Bendix Labeit, Sriramya Lapa, Sonja Suntrup-Krueger and Rainer Dziewas

    Citation: Neurological Research and Practice 2020 2:9

    Content type: Research article

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  34. Cerebrospinal fluid (CSF) analysis is important for detecting inflammation of the nervous system and the meninges, bleeding in the area of the subarachnoid space that may not be visualized by imaging, and the ...

    Authors: H. Tumani, H. F. Petereit, A. Gerritzen, C. C. Gross, A. Huss, S. Isenmann, S. Jesse, M. Khalil, P. Lewczuk, J. Lewerenz, F. Leypoldt, N. Melzer, S. G. Meuth, M. Otto, K. Ruprecht, E. Sindern…

    Citation: Neurological Research and Practice 2020 2:8

    Content type: Guidelines

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  35. Stroke is the leading cause of acquired disability in western societies. (Motor) cognitive deficits like apraxia significantly contribute to disability after stroke, harming activities of daily living and reha...

    Authors: Nina N. Kleineberg, Monika K. Richter, Ingrid Becker, Peter H. Weiss and Gereon R. Fink

    Citation: Neurological Research and Practice 2020 2:7

    Content type: Clinical trial protocol

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  36. Over the past decade increasing scientific progress in the field of autoantibody–mediated neurological diseases was achieved. Movement disorders are a frequent and often prominent feature in such diseases whic...

    Authors: Felix Gövert, Frank Leypoldt, Ralf Junker, Klaus-Peter Wandinger, Günther Deuschl, Kailash P. Bhatia and Bettina Balint

    Citation: Neurological Research and Practice 2020 2:6

    Content type: Review

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  37. We present the case of an 18 year old Caucasian with known celiac disease, who suffered a severe first attack of acute intermittent porphyria (AIP) with neuropsychiatric symptoms, severe tetraparesis and respi...

    Authors: Sebastian Nunnemann, Christoph Uibel, Petra Budig and Mathias Mäurer

    Citation: Neurological Research and Practice 2020 2:2

    Content type: Letter to the editor

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  38. Antibody-mediated and paraneoplastic autoimmune encephalitides (AE) present with a broad spectrum of clinical symptoms. They often lead to progressing inflammatory changes of the central nervous system with su...

    Authors: Rosa Rössling and Harald Prüss

    Citation: Neurological Research and Practice 2020 2:1

    Content type: Standard operating procedure

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  39. Autoimmune encephalitides with neural and glial antibodies have become an attractive field in neurology because the antibodies are syndrome-specific, explain the pathogenesis, indicate the likelihood of an und...

    Authors: C. G. Bien and C. I. Bien

    Citation: Neurological Research and Practice 2020 2:4

    Content type: Review

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  40. Many stroke survivors suffer recurrent stroke because paroxysmal atrial fibrillation (AF) was missed and no preventive anticoagulation initiated. This prospective cohort study determined the added diagnostic y...

    Authors: Stefan Knecht, Sebastian Petsch, Paulus Kirchhof and Bettina Studer

    Citation: Neurological Research and Practice 2019 1:41

    Content type: Research article

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  41. Multiple sclerosis is one of the most prevalent neurological diseases in young adults affecting over 2 million people worldwide. Alemtuzumab is a highly effective therapy in relapsing remitting MS. Alemtuzumab...

    Authors: Laura Bierhansl, Tobias Ruck, Steffen Pfeuffer, Catharina C. Gross, Heinz Wiendl and Sven G. Meuth

    Citation: Neurological Research and Practice 2019 1:40

    Content type: Clinical trial protocol

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  42. Comprehensive administrative data on TIA and stroke cases and treatment modalities are fundamental for improving structural conditions and adjusting future strategies of stroke care.

    Authors: Jens Eyding, Dirk Bartig, Ralph Weber, Aristeidis H. Katsanos, Christian Weimar, Werner Hacke and Christos Krogias

    Citation: Neurological Research and Practice 2019 1:39

    Content type: Research article

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  43. To date, specific therapeutic approaches to expedite recovery from apraxic deficits after left hemisphere (LH) stroke remain sparse. Thus, in this pilot study we evaluated the effect of anodal transcranial dir...

    Authors: Jana M. Ant, Eva Niessen, Elisabeth I. S. Achilles, Jochen Saliger, Hans Karbe, Peter H. Weiss and Gereon R. Fink

    Citation: Neurological Research and Practice 2019 1:38

    Content type: Research article

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  44. Acute febrile neutrophilic dermatosis (Sweet‘s syndrome) is a dermatological entity, which may be associated with malignancies, drugs, and infections and which is characterized by high fever, elevated neutroph...

    Authors: Elgin Hoffmann, Christian Boßelmann, Stephan Forchhammer, Holger Lerche and Tobias Freilinger

    Citation: Neurological Research and Practice 2019 1:36

    Content type: Letter to the editor

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