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  1. External ventricular drains (EVD) are commonly used in aneurysmal subarachnoid hemorrhage (aSAH) patients and can be life-saving by diverting cerebrospinal fluid. However, the overall relationship between EVD ...

    Authors: Sarah E. Nelson, Jose I. Suarez, Alexander Sigmon, Jun Hua, Casey Weiner, Haris I. Sair and Robert D. Stevens
    Citation: Neurological Research and Practice 2022 4:25
    Content type: Research article Published on:

  2. A 71-year-old male patient was diagnosed with LGI1 encephalopathy 4 weeks following a first ChAdOx1 nCov-19 vaccination. Extensive work-up including analysis of CSF and PET examination did not reveal a tangibl...

    Authors: Tamara Garibashvili and Josef Georg Heckmann
    Citation: Neurological Research and Practice 2022 4:24
    Content type: Letter to the editor Published on:

  3. Extracranial artery dissection involving either internal carotid artery or vertebral artery is a major cause of stroke in adults under 50 years of age. There is no conclusive evidence whether antiplatelets or ...

    Authors: Ei Zune The, Ne Naing Lin, Ching Jocelyn Chan, Jason Cher Wei Loon, Benjamin Yong-Qiang Tan, Chee Seong Raymond Seet, Hock Luen Teoh, Joy Vijayan and Leong Litt Leonard Yeo
    Citation: Neurological Research and Practice 2022 4:23
    Content type: Review Published on:

  4. In Dravet syndrome (DS), a rare epileptic and developmental encephalopathy, the effectiveness of a new treatment is predominantly measured in terms of seizure frequency. However, this may not fully capture the...

    Authors: Adam Strzelczyk, Gerhard Kurlemann, Thomas Bast, Ulrich Bettendorf, Gerhard Kluger, Thomas Mayer, Bernd A. Neubauer, Tilman Polster, Sarah von Spiczak, Regina Trollmann, Markus Wolff, Toby Toward, Jens Gruenert, Eddie Gibson, Clive Pritchard, Joe Carroll…
    Citation: Neurological Research and Practice 2022 4:22
    Content type: Research article Published on:

  6. Isocitrate dehydrogenase (IDH) mutations are disease-defining mutations in IDH-mutant astrocytomas and IDH-mutant and 1p/19q-codeleted oligodendrogliomas. In more than 80% of these tumors, point mutations in I...

    Authors: Lukas Bunse, Anne-Kathleen Rupp, Isabel Poschke, Theresa Bunse, Katharina Lindner, Antje Wick, Jens Blobner, Martin Misch, Ghazaleh Tabatabai, Martin Glas, Oliver Schnell, Jens Gempt, Monika Denk, Guido Reifenberger, Martin Bendszus, Patrick Wuchter…
    Citation: Neurological Research and Practice 2022 4:20
    Content type: Clinical trial protocol Published on:

  7. Optimal treatment of intracranial stenoses in varicella zoster virus (VZV)-associated vasculitis is unknown. This study aims to evaluate the merits and potential pitfalls of a specific therapeutic strategy, in...

    Authors: Markus Kraemer, Daniel Strunk, Jana Becker, Roland Veltkamp and Peter Berlit
    Citation: Neurological Research and Practice 2022 4:18
    Content type: Research article Published on:

  8. Residents play an important role in the clinical training of medical students, spending up to 25% of their daily work teaching. In the US medical curriculum didactic courses for residents already exist and the...

    Authors: Anne-Sophie Biesalski, Lars Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, Franziska Maria Ippen and Friederike Schmidt-Graf
    Citation: Neurological Research and Practice 2022 4:17
    Content type: Research article Published on:

  9. The use of direct oral anticoagulants (DOAC) has increased sharply and DOAC are the oral anticoagulant therapy (OAT) of choice for the majority of patients with newly-diagnosed atrial fibrillation. Intracrania...

    Authors: Waltraud Pfeilschifter, Edelgard Lindhoff-Last, Ali Alhashim, Barbara Zydek, Simone Lindau, Stavros Konstantinides, Oliver Grottke, Ulrike Nowak-Göttl, Christian von Heymann, Ingvild Birschmann, Jan Beyer-Westendorf, Patrick Meybohm, Andreas Greinacher and Eva Herrmann
    Citation: Neurological Research and Practice 2022 4:16
    Content type: Research article Published on:

  11. Anti-NMDA-receptor (anti-NMDAR) encephalitis is often associated with ovarian teratoma (OT). The best management of anti-NMDAR encephalitis patients with normal imaging studies (pelvic ultrasound/MRI) but clin...

    Authors: Christoph Cirkel, Anna Cirkel, Georg Royl, Alex Frydrychowicz, Lars Tharun, Steffen Deichmann, Achim Rody, Thomas F. Münte and Björn Machner
    Citation: Neurological Research and Practice 2022 4:15
    Content type: Letter to the editor Published on:

  12. The WHO estimates that each year 5 million people are left permanently disabled after stroke. Adjuvant treatments to promote the effects of rehabilitation are urgently needed. Cortical excitability and neuropl...

    Authors:
    Citation: Neurological Research and Practice 2022 4:14
    Content type: Clinical trial protocol Published on:

  13. Early prehospital stroke identification is crucial for goal directed hospital admission especially in rural areas. However, clinical prehospital stroke scales are designed to identify any stroke but cannot suf...

    Authors: Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S. Liebeskind and Felix Schlachetzki
    Citation: Neurological Research and Practice 2022 4:13
    Content type: Research article Published on:

  14. Sickle cell disease (SCD) is one of the most prevalent monogenetic diseases worldwide and one of the most serious complications is stroke. Transcranial Doppler (TCD) demonstrated to be highly predictive for an...

    Authors: Sylvia Thurn, Katharina Kleinschmidt, Irena Kovacic, Christina Wendl, Ralf A. Linker, Selim Corbacioglu and Felix Schlachetzki
    Citation: Neurological Research and Practice 2022 4:12
    Content type: Research article Published on:

  16. In this letter we raise several concerns regarding the interesting article by Walter and Krämer about rhomb-encephalitis as a complication two months after the vaccination with an mRNA-based SARS-CoV_2 vaccine...

    Authors: Josef Finsterer, Fulvio A. Scorza, Carla A. Scorza and Ana C. Fiorini
    Citation: Neurological Research and Practice 2022 4:10
    Content type: Letter to the editor Published on:

  17. Parkinson’s disease (PD) is a progressive, neurodegenerative disorder. In the advanced stages it can result in severe disability despite optimal treatment. Data suggests heterogeneous classification of PD stag...

    Authors: David J. Pedrosa, Florin Gandor, Wolfgang H. Jost, Carolin Arlt, Koray Onuk and Lars Timmermann
    Citation: Neurological Research and Practice 2022 4:9
    Content type: Research article Published on:

  18. Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by a prolonged, but self-limiting segmental cerebral vasoconstriction. Neurological outcomes vary, but can be severe. The clinical hallmark...

    Authors: Daniel Strunk, Roland Veltkamp, Sven G. Meuth, René Chapot and Markus Kraemer
    Citation: Neurological Research and Practice 2022 4:8
    Content type: Research article Published on:

  19. Based on demographical trends and the expected worldwide increase in the number of individuals with atrial fibrillation, the rate of patients who are on oral anticoagulation therapy for secondary prevention of...

    Authors: Pawel Kermer, Peter D. Schellinger, Peter A. Ringleb and Martin Köhrmann
    Citation: Neurological Research and Practice 2022 4:7
    Content type: Standard operating procedure Published on:

  20. This correspondence comments on a published article presenting a case of rhombencephalitis following SARS-CoV-2-vaccination with the mRNA vaccine BNT162b2 (Pfizer/BioNTech). We also present the case of a 47-ye...

    Authors: Maria Ioanna Stefanou, Eleni Karachaliou, Maria Chondrogianni, Christos Moschovos, Eleni Bakola, Aikaterini Foska, Konstantinos Melanis, Elisabeth Andreadou, Konstantinos Voumvourakis, Matilda Papathanasiou, Eleni Boutati and Georgios Tsivgoulis
    Citation: Neurological Research and Practice 2022 4:6
    Content type: Letter to the editor Published on:

  21. By whole-exome sequencing, we found the heterozygous POLG variant c.3542G>A; p.Ser1181Asn in a family of four affected individuals, presenting with a mixed neuro-myopathic phenotype. The variant is located within...

    Authors: Maike F. Dohrn, Corina Heller, Diana Zengeler, Carolin D. Obermaier, Saskia Biskup, Joachim Weis, Stefan Nikolin, Kristl G. Claeys, Ulrike Schöne, Danique Beijer, Natalie Winter, Pascal Achenbach, Burkhard Gess, Jörg B. Schulz and Lejla Mulahasanovic
    Citation: Neurological Research and Practice 2022 4:5
    Content type: Letter to the editor Published on:

  22. Nearly one in three unconscious cardiac arrest survivors experience post-anoxic status epilepticus (PASE). Historically, PASE has been deemed untreatable resulting in its exclusion from status epilepticus clin...

    Authors: Carolina B. Maciel, Fernanda J. P. Teixeira, Katie J. Dickinson, Jessica C. Spana, Lisa H. Merck, Alejandro A. Rabinstein, Robert Sergott, Guogen Shan, Guanhong Miao, Charles A. Peloquin, Katharina M. Busl and Lawrence J. Hirsch
    Citation: Neurological Research and Practice 2022 4:4
    Content type: Clinical trial protocol Published on:

  23. The diagnosis of chronic lyme neuroborreliosis can be a challenge even for experienced neurologists. The clinical picture may be multifaceted, including polyradiculitis to cranial nerve palsies, meningitis, en...

    Authors: Deborah K. Erhart, Vera Bracknies, Susanne Lutz-Schuhbauer, Sonja Wigand and Hayrettin Tumani
    Citation: Neurological Research and Practice 2022 4:3
    Content type: Letter to the editor Published on:

  24. Treatment with CD19 chimeric antigen receptor (CAR) T cells is an innovative therapeutic approach for patients with relapsed/refractory diffuse large B cell lymphoma (r/rDLBCL) and B-lineage acute lymphoblasti...

    Authors: Nora Möhn, Viktoria Bonda, Lea Grote-Levi, Victoria Panagiota, Tabea Fröhlich, Christian Schultze-Florey, Mike P. Wattjes, Gernot Beutel, Matthias Eder, Sascha David, Sonja Körner, Günter Höglinger, Martin Stangel, Arnold Ganser, Christian Koenecke and Thomas Skripuletz
    Citation: Neurological Research and Practice 2022 4:1
    Content type: Research article Published on:

  25. Major efforts have been made in the last decade to develop and improve therapies for proximal spinal muscular atrophy (SMA). The introduction of Nusinersen/Spinraza™ as an antisense oligonucleotide therapy, On...

    Authors: Sibylle Jablonka, Luisa Hennlein and Michael Sendtner
    Citation: Neurological Research and Practice 2022 4:2
    Content type: Review Published on:

  26. Impaired motor functions after stroke are common and negatively affect patients' activities of daily living and quality of life. In particular, hand motor function is essential for daily activities, but often ...

    Authors: Thies Ingwersen, Silke Wolf, Gunnar Birke, Eckhard Schlemm, Christian Bartling, Gabriele Bender, Alfons Meyer, Achim Nolte, Katharina Ottes, Oliver Pade, Martin Peller, Jochen Steinmetz, Christian Gerloff and Götz Thomalla
    Citation: Neurological Research and Practice 2021 3:66
    Content type: Research article Published on:

  27. Deep brain stimulation of the internal globus pallidus is an effective treatment for dystonia. However, there is a large variability in clinical outcome with up to 25% non-responders even in highly selected pr...

    Authors: Florian Lange, Jonas Roothans, Tim Wichmann, Götz Gelbrich, Christoph Röser, Jens Volkmann and Martin Reich
    Citation: Neurological Research and Practice 2021 3:65
    Content type: Clinical trial protocol Published on:

  28. Appropriate treatment of stroke immediately after its onset contributes to the improved chances, while delay in hospitalisation affects stroke severity and fatality. This study aimed to determine the impact of...

    Authors: Takuaki Tani, Shinobu Imai and Kiyohide Fushimi
    Citation: Neurological Research and Practice 2021 3:64
    Content type: Research article Published on:

  29. With the increased efficacy of stroke treatments, diagnosis and specific treatment needs of patients with post-stroke seizures (PSS) and post-stroke epilepsy have become increasingly important. PSS can complic...

    Authors: Johann Philipp Zöllner, Friedhelm C. Schmitt, Felix Rosenow, Konstantin Kohlhase, Alexander Seiler, Adam Strzelczyk and Hermann Stefan
    Citation: Neurological Research and Practice 2021 3:63
    Content type: Review Published on:

  31. Patients with multiple sclerosis receiving ocrelizumab-treatment are in desperate need of a protection against SARS-CoV-2 infection.

    Authors: Mosche Pompsch, Neslinur Fisenkci, Peter A. Horn, Markus Kraemer and Monika Lindemann
    Citation: Neurological Research and Practice 2021 3:60
    Content type: Research article Published on:

  32. There have been numerous classification systems to diagnose corresponding myositis subtypes and select appropriate therapeutic measures. However, the lack of a broad consensus on diagnostic criteria has led to...

    Authors: Jan Zoske, Udo Schneider, Elise Siegert, Felix Kleefeld, Corinna Preuße, Werner Stenzel and Katrin Hahn
    Citation: Neurological Research and Practice 2021 3:59
    Content type: Research article Published on:

  34. Hereditary transthyretin (TTR) amyloidosis (ATTRv) is an autosomal dominant, systemic disease transmitted by amyloidogenic mutations in the TTR gene. To prevent the otherwise fatal disease course, TTR stabilizers...

    Authors: Maike F. Dohrn, Jessica Medina, Karmele R. Olaciregui Dague and Ernst Hund
    Citation: Neurological Research and Practice 2021 3:57
    Content type: Review Published on:

  35. Calculation of levodopa-equivalent dose in Parkinson’s disease has become common in research, but is also a useful tool in clinical practice, especially when initiating device-aided treatments (deep brain stim...

    Authors: D. Nyholm and W. H. Jost
    Citation: Neurological Research and Practice 2021 3:58
    Content type: Letter to the editor Published on:

  36. Asymptomatic carotid artery stenosis (ACS) can be treated with carotid endarterectomy (CEA), carotid artery stenting (CAS), or best medical treatment (BMT) only. For all treatment options, optimization of vasc...

    Authors: Tilman Reiff, Hans-Henning Eckstein, Ulrich Mansmann, Olav Jansen, Gustav Fraedrich, Harald Mudra, Werner Hacke and Peter Arthur Ringleb
    Citation: Neurological Research and Practice 2021 3:62
    Content type: Research article Published on:

  37. Among congenital anomalies of the carotid artery circulation, the presence of a non-bifurcating carotid artery is extremely rare. Relevant cases with unilateral non-bifurcating carotid artery have scarcely bee...

    Authors: Lina Palaiodimou, Georgia Papagiannopoulou, Aikaterini Theodorou, Eleni Bakola, Maria Chondrogianni, Maria-Ioanna Stefanou, Elizabeth Andreadou, Stefanos Lachanis and Georgios Tsivgoulis
    Citation: Neurological Research and Practice 2021 3:55
    Content type: Letter to the editor Published on:

  38. Recently, antibodies against the alpha isoform of the glial-fibrillary-acidic-protein (GFAPα) were identified in a small series of patients with encephalomyelitis. Coexisting autoantibodies (NMDA receptor, GAD...

    Authors: Anna Cirkel, Klaus-Peter Wandinger, Claudia Ditz, Jan Leppert, Lars Hanker, Christoph Cirkel, Alexander Neumann, Jan Brocke, Romana Höftberger, Lars Komorowski, Sven Perner, Frank Leypoldt, Tobias Wagner-Altendorf, Thomas F. Münte and Georg Royl
    Citation: Neurological Research and Practice 2021 3:48
    Content type: Research article Published on:

  39. The ChAdOx1 nCoV-19 adenoviral vector vaccine to prevent contracting Covid-19 caused by infection with SARS-CoV-2 has been associated with vaccine-induced immune thrombotic thrombocytopenia (VITT) primarily le...

    Authors: Yasemin Goereci, Nina N. Kleineberg, Marie Madlener, Hannah Neuschmelting, Gereon R. Fink, Clemens Warnke and Henning Stetefeld
    Citation: Neurological Research and Practice 2021 3:52
    Content type: Letter to the editor Published on:

  40. The modified Boston criteria (mBC) define the probability for the diagnosis of cerebral amyloid angiopathy (CAA). Its initial clinical presentation differs from asymptomatic cerebral microbleedings (cMBs), acu...

    Authors: Andrea Wagner, Christiane Groetsch, Sibylle Wilfling, Karl-Michael Schebesch, Mustafa Kilic, Marjan Nenkov, Christina Wendl, Ralf A. Linker and Felix Schlachetzki
    Citation: Neurological Research and Practice 2021 3:51
    Content type: Research article Published on:

  41. Thrombus histology has become a potential diagnostic tool for the etiology assessment of patients with ischemic stroke caused by embolic proximal vessel occlusion. We validated a classification rule that diffe...

    Authors: Julika Ribbat-Idel, Florian Stellmacher, Florian Jann, Nicolas Kalms, Inke R. König, Marcus Ohlrich, Georg Royl, Stefan Klotz, Thomas Kurz, Andrè Kemmling and Florian C. Roessler
    Citation: Neurological Research and Practice 2021 3:50
    Content type: Research article Published on:

  42. More patients with left-hemispheric than right-hemispheric strokes are admitted to hospitals. This is due to the easier recognition of cortical symptoms of the dominant-hemisphere. The thalamus constitutes a “...

    Authors: Martin A. Schaller-Paule, Ariane Martinez Oeckel, Jan-Rüdiger Schüre, Fee Keil, Elke Hattingen, Christian Foerch and Maximilian Rauch
    Citation: Neurological Research and Practice 2021 3:49
    Content type: Research article Published on:

  44. Post stroke management has moved into the focus as it represents the only way to secure acute treatment effects in the long term. Due to individual courses, post stroke management appears rather challenging an...

    Authors: Dominik Michalski, Alexander Prost, Till Handel, Max Schreiber, Jean-Baptiste Tylcz, Daniela Geisler, Daniela Urban, Stephanie Schramm, Stefan Lippmann, Jenny Gullnick, Thomas Neumuth, Joseph Classen and Galina Ivanova
    Citation: Neurological Research and Practice 2021 3:53
    Content type: Clinical trial protocol Published on:

    The Commentary to this article has been published in Neurological Research and Practice 2021 3:54

  45. Measures taking aim at minimizing the risk of coronavirus transmission and fear of infection may affect decisions to seek care for other medical emergency conditions. The purpose of this analysis was to analyz...

    Authors: Johannes A. R. Pfaff, Marcial E. Harlan, Günter Pfaff, Alexander Hubert and Martin Bendszus
    Citation: Neurological Research and Practice 2021 3:47
    Content type: Research article Published on:

  46. We aimed to identify groups of patients with similar health status after stroke, assessed by patient reported outcome measures (PROMs), to improve initial risk stratification.

    Authors: D. Leander Rimmele, Theresa Schrage, Lisa Lebherz, Levente Kriston, Christian Gerloff, Martin Härter and Götz Thomalla
    Citation: Neurological Research and Practice 2021 3:43
    Content type: Research article Published on:

  47. Since the coronavirus disease 2019 (COVID-19) has risen, several risk factors have been identified, predicting a worse outcome. It has been speculated that patients with Multiple sclerosis (MS) have an increas...

    Authors: Daniel Richter, Simon Faissner, Dirk Bartig, Lars Tönges, Kerstin Hellwig, Ilya Ayzenberg, Christos Krogias and Ralf Gold
    Citation: Neurological Research and Practice 2021 3:42
    Content type: Research article Published on:

  48. To prospectively analyze factors associated with detecting epileptogenic lesions on MRI within the work-sharing process of neurologists, epileptologists, radiologists and neuroradiologists.

    Authors: Tim Wehner, Philippe Weckesser, Steven Schulz, Annika Kowoll, Sebastian Fischer, Jessica Bosch, Leonie Weinhold, Rolf Fimmers, Matthias Schmid and Jörg Wellmer
    Citation: Neurological Research and Practice 2021 3:41
    Content type: Research article Published on:
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