| First line |
| Corticosteroids | No details on doses or durations given |
| Plasma exchange |
| Intravenous immunoglobulins |
| Second line (if first line did not work within 10 daysa) |
| Rituximab | 4 × 375 mg/m2 i.v., weekly administration |
| Cyclophosphamideb | 750 mg/m2 i.v. per month |
- aThis has been said for anti-NMDAR encephalitis. In other, less severe forms of autoimmune encephalitis, one may wait longer before one moves on to second-line therapy. bIn pediatric patients, cyclophosphamide is less frequently used compared to rituximab
