Skip to main content

Table 3 A, B and C. Accuracy of the ph-ICH score for the prediction of ICH and AIS/TIA/SM as well as ICH and AIS patients. Table A summarizes the results of AIS/TIA/SM patients and Table B of the AIS patients for the derivation cohort; Table C shows the results of AIS patients for the validation cohort

From: Probability assessment of intracerebral hemorrhage in prehospital emergency patients

A) Derivation cohort
ph-ICH score
SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10)
Cohen’s d
(pooled SD)
1.2 (0.9)
ph-ICH score Sensitivity Specificity PPV NPV +LR No. of AIS/TIA/SM patients No. of ICH patients
≥1.5 0.50 0.80 0.17 0.95 2.5 76 (19.8%) 16 (50.0%)
≥2.0 0.38 0.88 0.21 0.94 3.1 46 (12.0%) 12 (37.5%)
≥2.5 0.28 0.96 0.38 0.94 7.2 15 (3.9%) 9 (28.1%)
≥3.0 0.25 0.97 0.44 0.94 9.6 10 (2.6%) 8 (25.0%)
≥3.5 0.13 1.00 0.80 0.93 48.0 1 (0.3%) 4 (12.5%)
B) Derivation cohort
ph-ICH score
SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10)
Cohen’s d
(pooled SD)
0.9 (0.9)
ph-ICH score Sensitivity Specificity PPV NPV +LR No. of AIS patients No. of ICH patients
≥1.5 0.50 0.73 0.21 0.91 1.9 60 (26.8%) 16 (50.0%)
≥2.0 0.38 0.83 0.24 0.90 2.3 37 (16.5%) 12 (37.5%)
≥2.5 0.28 0.95 0.45 0.90 5.7 11 (4.9%) 9 (28.1%)
≥3.0 0.25 0.96 0.47 0.90 6.2 9 (4.0%) 8 (25.0%)
≥3.5 0.13 1.00 0.80 0.89 28.0 1 (0.4%) 4 (12.5%)
C) Validation cohort
ph-ICH score
SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10)
Cohen’s d
(pooled SD)
1.4 (0.7)
ph-ICH score Sensitivity Specificity PPV NPV +LR No. of AIS patients No. of ICH patients
≥1.5 0.52 0.87 0.34 0.93 3.9 33 (13.1%) 17 (51.5%)
≥2.0 0.39 0.94 0.46 0.92 6.6 15 (6.0%) 13 (39.4%)
≥2.5 0.24 0.98 0.62 0.91 12.2 5 (2.0%) 8 (24.2%)
≥3.0 0.12 1.00 1.00 0.90 n. a. 0 4 (12.1%)
≥3.5 0.03 1.00 1.00 0.89 n. a. 0 1 (3.0%)
  1. AIS Acute ischemic stroke, ICH Intracerebral hemorrhage, LOC Level of consciousness, +LR Positive likelihood ratio (sensitivity/(1-specificity)), n. a. Not available (division by 0), NIHSS National Institutes of Health Stroke Scale, No. Number, NPV Negative predictive value, ph-ICH score Prehospital-intracerebral hemorrhage score, PPV Positive predictive value, SD Standard deviation, SM Stroke mimic, SP Systolic blood pressure, TIA Transient ischemic attack