Table 3 A, B and C. Accuracy of the ph-ICH score for the prediction of ICH and AIS/TIA/SM as well as ICH and AIS patients. Table A summarizes the results of AIS/TIA/SM patients and Table B of the AIS patients for the derivation cohort; Table C shows the results of AIS patients for the validation cohort
From: Probability assessment of intracerebral hemorrhage in prehospital emergency patients
A) Derivation cohort | |||||||
ph-ICH score SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10) | Cohen’s d (pooled SD) 1.2 (0.9) | ||||||
ph-ICH score | Sensitivity | Specificity | PPV | NPV | +LR | No. of AIS/TIA/SM patients | No. of ICH patients |
≥1.5 | 0.50 | 0.80 | 0.17 | 0.95 | 2.5 | 76 (19.8%) | 16 (50.0%) |
≥2.0 | 0.38 | 0.88 | 0.21 | 0.94 | 3.1 | 46 (12.0%) | 12 (37.5%) |
≥2.5 | 0.28 | 0.96 | 0.38 | 0.94 | 7.2 | 15 (3.9%) | 9 (28.1%) |
≥3.0 | 0.25 | 0.97 | 0.44 | 0.94 | 9.6 | 10 (2.6%) | 8 (25.0%) |
≥3.5 | 0.13 | 1.00 | 0.80 | 0.93 | 48.0 | 1 (0.3%) | 4 (12.5%) |
B) Derivation cohort | |||||||
ph-ICH score SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10) | Cohen’s d (pooled SD) 0.9 (0.9) | ||||||
ph-ICH score | Sensitivity | Specificity | PPV | NPV | +LR | No. of AIS patients | No. of ICH patients |
≥1.5 | 0.50 | 0.73 | 0.21 | 0.91 | 1.9 | 60 (26.8%) | 16 (50.0%) |
≥2.0 | 0.38 | 0.83 | 0.24 | 0.90 | 2.3 | 37 (16.5%) | 12 (37.5%) |
≥2.5 | 0.28 | 0.95 | 0.45 | 0.90 | 5.7 | 11 (4.9%) | 9 (28.1%) |
≥3.0 | 0.25 | 0.96 | 0.47 | 0.90 | 6.2 | 9 (4.0%) | 8 (25.0%) |
≥3.5 | 0.13 | 1.00 | 0.80 | 0.89 | 28.0 | 1 (0.4%) | 4 (12.5%) |
C) Validation cohort | |||||||
ph-ICH score SP ≥ 180 + NIHSS LOC ≥ 1 + NIHSSshort (sum of the following NIHSS items: LOC, following commands, visual field, motor weakness of arm or leg, sensory disturbance divided by 10) | Cohen’s d (pooled SD) 1.4 (0.7) | ||||||
ph-ICH score | Sensitivity | Specificity | PPV | NPV | +LR | No. of AIS patients | No. of ICH patients |
≥1.5 | 0.52 | 0.87 | 0.34 | 0.93 | 3.9 | 33 (13.1%) | 17 (51.5%) |
≥2.0 | 0.39 | 0.94 | 0.46 | 0.92 | 6.6 | 15 (6.0%) | 13 (39.4%) |
≥2.5 | 0.24 | 0.98 | 0.62 | 0.91 | 12.2 | 5 (2.0%) | 8 (24.2%) |
≥3.0 | 0.12 | 1.00 | 1.00 | 0.90 | n. a. | 0 | 4 (12.1%) |
≥3.5 | 0.03 | 1.00 | 1.00 | 0.89 | n. a. | 0 | 1 (3.0%) |