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Table 2 Recommendations for diagnostic LP in thrombocytopenia (see also cross-sectional guideline of the Bundesärztekammer on therapy with blood components and plasma derivatives (https://www.bundesaerztekammer.de/fileadmin/user_upload/downloads/pdf-Ordner/WB/QLL_Haemotherapie-englisch.pdf))

From: S1 guidelines “lumbar puncture and cerebrospinal fluid analysis” (abridged and translated version)

Thrombocyte count /μL

Procedure for a planned LP

> 50,000

If there are no other contraindications.

10,000–50,000

Relative contraindication. An increased risk of bleeding is to be expected. Substitute thrombocytes if necessary.

< 10,000

Absolute contraindication. Thrombocyte substitution before LP mandatory.