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Table 1 Baseline characteristics

From: Mechanical thrombectomy in patients with cervical artery dissection and stroke in the anterior or posterior circulation – a multicenter analysis from the German Stroke Registry

  No CAD, n = 2527 CAD, n = 62 P
Demographic
 Age – years, median (IQR), n 76 (65–82), n = 2527 51 (43–57), n = 62 <.001
 Female, % (n) 50.9% (1286) 25.8% (16) <.001
Pre-stroke mRS, % (n)
 0 68.0% (1652) 95.2% (59) <.001
 1 12.8% (310) 0% (0)
 2 8.3% (201) 3.2% (2)
 3 6.0% (145) 1.6% (1)
 4 3.5% (86) 0% (0)
 5 1.4% (35) 0% (0)
Current smoking, % (n) 15.0% (332) 24.1% (13) .160
Clinical
 NIHSS, median (IQR), n 15 (10–19), n = 2527 14 (7–17), n = 62 .107
Medical history, % (n)
 Hypertension 76.8% (1925) 25.8% (16) <.001
 Diabetes mellitus 21.3% (535) 4.8% (3) <.001
 Dyslipidemia 34.1% (854) 17.7% (11) .006
 Atrial fibrillation 41.9% (1049) 1.6% (1) <.001
Medication, % (n)
 Antiplatelet 33.5% (822) 17.7% (11) .009
 Anticoagulation 21.0% (515) 1.6% (1) <.001
Etiology, % (n)
 Cardioembolism 51.7% (1307)
 Dissection 100.0% (62)
 Large-artery atherosclerosis 25.9% (654)
 Small-vessel occlusion 0.0% (1)
 Stroke of other determined etiology 4.8% (122)
 Stroke of undetermined etiology 17.5% (443)
Direct-to-center, % (n) 52.0% (1313) 54.8% (34) .701
Symptom onset known, % (n) 61.5% (1553) 74.2% (46) .047
Time from symptom onset to admission – min, median (IQR), n 127 (59–206), n = 1553 119 (54–185), n = 46 .728
Time from last-seen-well to admission – min, median (IQR), n 357 (202–685), n = 974 283 (200–339), n = 16 .163
Radiological
 ASPECTS, median (IQR), n 9 (7–10), n = 1904 8 (6–10), n = 37 .025
 Occluded vessel, % (n)
  ICA 24.5% (614) 45.2% (28) <.001
  MCA, M1 56.7% (1423) 29.0% (18) <.001
  MCA, M2 17.7% (444) 19.4% (12) .420
  ACA 2.5% (62) 0.0% (0) .403
  BA 10.2% 255) 19.4% (12) .032
  VA 1.7% (42) 17.7% (11) <.001
  PCA 2.2% (55) 1.6% (1) 1.000
mTICI before thrombectomy, % (n)
 0 85.9% (2088) 86.7% (52) .801
 1 4.8% (117) 5.0% (3)
 2a 2.1% (50) 1.7% (1)
 2b 3.1% (75) 5.0% (3)
 3 4.2% (102) 1.7% (1)
Extracranial ICA stenosis (> 70%)
ipsilateral to intracranial vessel
occlusion, % (n/n)
14.1% (334) 46.7% (28) <.001
  1. CAD stands for cervical artery dissection, IQR Interquartile range, mRS Modified Rankin scale, NIHSS National Institutes of Health Stroke Scale, ASPECTS Alberta Stroke Program Early CT Score, ICA Internal carotid artery, ACA Anterior cerebral artery, BA Basilar artery, VA Vertebral artery, PCA Posterior cerebral artery, mTICI Modified Treatment in Cerebral Infarction