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Fig. 2 | Neurological Research and Practice

Fig. 2

From: Treatment of progressive multiple sclerosis with high-dose all-trans retinoic acid – no clear evidence of positive disease modifying effects

Fig. 2

High heterogeneity in CD4 / CD8 T cell subsets with no obvious alteration by ATRA. Central memory CD4+ T cells (CD4+ Tcm), naïve CD4+ T cells and effector memory CD4+ T cells (CD4+ Tem) as well as central memory CD8 T cells (CD8+ Tcm), naive CD8+ T cells and effector memory CD8+ T cells (CD8+ Tem) were tested before (green dots), during (black dots) and in the follow-up period after (blue dots) treatment with ATRA, red dots indicate end of treatment. High heterogeneity was observed with no evidence of direct alteration by induction of treatment. Grey lines indicate range of normal values (mean +/− 2*SD) obtained as reference from 10 healthy controls. All tests showed no significance (p < 0,05) in Friedman-test with Dunn’s post-hoc test

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Neurological Research and Practice

ISSN: 2524-3489

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