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Table 1 Proportion of patients with sufficient implementation of BMT goals; visit D30 to A1; n = 513

From: Successful implementation of best medical treatment for patients with asymptomatic carotid artery stenosis within a randomized controlled trial (SPACE-2)

  CEA (% [n]) CAS (% [n]) BMT (% [n]) total (%[n]) p
Blood pressure ≤ 130/85 mmHg1
 D30 23.5% (44) 26.6% (47) 22.9% (24) 24.5% (115) 0.772
 M6 25.4% (45) 30.6% (53) 31.1% (33) 28.7% (131) 0.461
 A1 25.7% (44) 29.8% (50) 30.1% (31) 28.3% (125) 0.638
Cholesterol < 200 mg/dl
 D30 69.6% (103) 79.2% (114) 83.1% (74) 76.4% (291) 0.036*
 M6 75.8% (116) 76.5% (114) 88.3% (83) 79.0% (313) 0.041*
 A1 74.5% (117) 77.1% (111) 87.5% (77) 78.4% (305) 0.054
LDL-cholesterol < 130 mg/dl2
 D30 69.9% (100) 75.9% (107) 77.3% (68) 73.9% (275) 0.372
 M6 72.8% (110) 71.9% (105) 82.6% (76) 74.8% (291) 0.140
 A1 75.0% (117) 76.8% (109) 75.9% (66) 75.8% (292) 0.939
HDL-cholesterol ≥ 40 mg/dl
 D30 76.7% (112) 76.8% (109) 80.5% (70) 77.6% (291) 0.766
 M6 76.7% (115) 80.1% (117) 78.5% (73) 78.4% (305) 0.768
 A1 79.7% (122) 77.1% (111) 78.4% (69) 78.4% (302) 0.857
Triglycerides < 150 mg/dl
 D30 64.8% (94) 66.4% (93) 63.6% (56) 65.1% (243) 0.907
 M6 57.9% (88) 66.0% (97) 75.3% (70) 65.1% (255) 0.021*
 A1 58.2% (89) 65.3% (94) 62.5% (55) 61.8% (238) 0.567
HbA1c < 7%
 D30 89.1% (123) 84.9% (118) 77.3% (68) 84.7% (309) 0.054
 M6 84.3% (118) 87.0% (120) 81.3% (74) 84.6% (312) 0.510
 A1 82.4% (126) 82.6% (119) 81.8% (72) 82.3% (317) 0.408
Quit smoking if smoker on D0
 D30 9.5% (13) 4.2% (6) 1.0% (1) 5.3% (20) 0.013±*
 M6 3.9% (5) 4.4% (6) 5.0% (5) 4.4% (16) 0.927
 A1 3.4% (4) 1.6% (2) 0 1.8% (6) 0.208 ±
Physical activity ≥ 30 min 3–5 times/week
 D30 52.4% (97) 49.4% (85) 66.7% (70) 54.5% (252) 0.015*
 M6 53.9% (96) 54.7% (94) 62.9% (66) 56.3% (256) 0.297
 A1 47.1% (81) 55.4% (93) 60.4% (61) 53.3% (235) 0.082
Sufficient weight reduction3 if BMI ≥ 25 on D0
 D30 5.1% (7) 3.0% (4) 5.7% (4) 4.4% (15) 0.583±
 M6 6.9% (9) 3.8% (5) 6.8% (5) 5.6% (19) 0.483
 A1 7.1% (9) 6.3% (8) 6.8% (5) 6.7% (22) 0.964
  1. BMI body mass index
  2. *Significant
  3. ±Fisher`s exact test
  4. Chi2-Test
  5. 1If comorbidity diabetes mellitus: ≤ 130/80 mmHg
  6. 2If comorbidity coronary heart disease: < 100 mg/dl
  7. 3If BMI 25–27.5: Weight reduction to BMI < 25, if BMI > 27.5: 10% weight reduction; D0: Screening visit; D30: Visit after 30 days; M6: Visit after six months; A1: Visit after one year