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Table 1 Proportion of patients with sufficient implementation of BMT goals; visit D30 to A1; n = 513

From: Successful implementation of best medical treatment for patients with asymptomatic carotid artery stenosis within a randomized controlled trial (SPACE-2)

 

CEA (% [n])

CAS (% [n])

BMT (% [n])

total (%[n])

p

Blood pressure ≤ 130/85 mmHg1

 D30

23.5% (44)

26.6% (47)

22.9% (24)

24.5% (115)

0.772

 M6

25.4% (45)

30.6% (53)

31.1% (33)

28.7% (131)

0.461

 A1

25.7% (44)

29.8% (50)

30.1% (31)

28.3% (125)

0.638

Cholesterol < 200 mg/dl

 D30

69.6% (103)

79.2% (114)

83.1% (74)

76.4% (291)

0.036*

 M6

75.8% (116)

76.5% (114)

88.3% (83)

79.0% (313)

0.041*

 A1

74.5% (117)

77.1% (111)

87.5% (77)

78.4% (305)

0.054

LDL-cholesterol < 130 mg/dl2

 D30

69.9% (100)

75.9% (107)

77.3% (68)

73.9% (275)

0.372

 M6

72.8% (110)

71.9% (105)

82.6% (76)

74.8% (291)

0.140

 A1

75.0% (117)

76.8% (109)

75.9% (66)

75.8% (292)

0.939

HDL-cholesterol ≥ 40 mg/dl

 D30

76.7% (112)

76.8% (109)

80.5% (70)

77.6% (291)

0.766

 M6

76.7% (115)

80.1% (117)

78.5% (73)

78.4% (305)

0.768

 A1

79.7% (122)

77.1% (111)

78.4% (69)

78.4% (302)

0.857

Triglycerides < 150 mg/dl

 D30

64.8% (94)

66.4% (93)

63.6% (56)

65.1% (243)

0.907

 M6

57.9% (88)

66.0% (97)

75.3% (70)

65.1% (255)

0.021*

 A1

58.2% (89)

65.3% (94)

62.5% (55)

61.8% (238)

0.567

HbA1c < 7%

 D30

89.1% (123)

84.9% (118)

77.3% (68)

84.7% (309)

0.054

 M6

84.3% (118)

87.0% (120)

81.3% (74)

84.6% (312)

0.510

 A1

82.4% (126)

82.6% (119)

81.8% (72)

82.3% (317)

0.408

Quit smoking if smoker on D0

 D30

9.5% (13)

4.2% (6)

1.0% (1)

5.3% (20)

0.013±*

 M6

3.9% (5)

4.4% (6)

5.0% (5)

4.4% (16)

0.927

 A1

3.4% (4)

1.6% (2)

0

1.8% (6)

0.208 ±

Physical activity ≥ 30 min 3–5 times/week

 D30

52.4% (97)

49.4% (85)

66.7% (70)

54.5% (252)

0.015*

 M6

53.9% (96)

54.7% (94)

62.9% (66)

56.3% (256)

0.297

 A1

47.1% (81)

55.4% (93)

60.4% (61)

53.3% (235)

0.082

Sufficient weight reduction3 if BMI ≥ 25 on D0

 D30

5.1% (7)

3.0% (4)

5.7% (4)

4.4% (15)

0.583±

 M6

6.9% (9)

3.8% (5)

6.8% (5)

5.6% (19)

0.483

 A1

7.1% (9)

6.3% (8)

6.8% (5)

6.7% (22)

0.964

  1. BMI body mass index
  2. *Significant
  3. ±Fisher`s exact test
  4. Chi2-Test
  5. 1If comorbidity diabetes mellitus: ≤ 130/80 mmHg
  6. 2If comorbidity coronary heart disease: < 100 mg/dl
  7. 3If BMI 25–27.5: Weight reduction to BMI < 25, if BMI > 27.5: 10% weight reduction; D0: Screening visit; D30: Visit after 30 days; M6: Visit after six months; A1: Visit after one year