Table 1 Characteristics of patients with large vessel occlusion, subdivided into those with and without prior stroke. For intergroup differences, chi-square test was used for binary variables and Mann-Whitney test for ordinal or numeric scaled variables, with a p-value < 0.05 considered significant and marked in bold. Abbreviations: NIHSS – National Institute of Health Stroke Scale, mRS – modified Rankin Scale

Age

70.8 ± 14.1

74.0 ± 11.7

0.04 (Mann-Whitney-Test)

Chi-Square

Posterior circulation %positive

62; 8.8%

13; 8.1%

0.84

Anterior circulation %positive

648; 91.7%

147; 91.9%

0.91

Sex %female

355; 50.2%

77; 48.1%

0.66

Died %

133; 18.8%

34; 21.3%

0.6

Etiology

Cryptogenic

176; 24.9%

19; 11.0%

< 0.01

Large-artery sclerosis

211; 29.9%

60; 37.5%

Cardioembolism

286; 40.5%

77; 48.1%

Others

33; 4.7%

4; 2.5%

Mechanical thrombectomy %yes

382; 54.0%

68; 42.5%

0.019

Systemic thrombolysis %yes

348; 49.2%

57; 35.6%

< 0.01

Oral anticoagulants %yes

100; 14.1%

41; 25.6%

< 0.01

Platelet aggregation inhibitor %yes

184; 26.0%

80; 50.0%

< 0.01

Statins %yes

147; 20.8%

81; 50.6%

< 0.01

Cholesterol ≥ 200 mg/dl at admission %yes

109; 19.9%

18; 14.5%

0.26

Diabetes mellitus %yes

120; 17.0%

55; 34.4%

< 0.01

Arterial hypertension %yes

561; 70.9%

137; 85.6%

< 0.01

Atrial fibrillation %yes

270; 38.2%

83; 51.9%

< 0.01

NIHSS at admission (median)

13 (6–18)

12 (6–17)

0.53 (Mann-Whitney-Test)

NIHSS at discharge (median)

3 (0–9)

4 (2–12)

0.04 (Mann-Whitney-Test)

mRS at admission

0 (0–1)

1 (0–3)

< 0.01 (Mann-Whitney-Test)

mRS at discharge

4 (1–5)

4 (2–6)

0.06 (Mann-Whitney-Test))