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Table 1 Major Clinical Trials targeting hematoma expansion with provided Time from onset to randomization

From: Hematoma expansion in intracerebral hemorrhage – the right target?

Major Trial

Time from onset to randomization

ICH Volume (ml)

HE (abs. ml)

FAST

Intervention: 161 ±37, mina

Control: 160 ±38, mina

I: 24 ± 26

C: 23 ± 26

I: 4.9 (2.9-7.0)

C: 7.5 (5.4–9.6)

PATCH

Intervention: n.a.

Control: n.a.

I: 13.1 (5.4–42.4)

C: 8.0 (4.4–25.8)

I: 2.01 (0.32–9.34)

C:1.16 (0.03–4.42)

TICH-2

I: 3.6 (2.6–5.1), h

C: 3.7 (2.6-5.0), h

I: 14.1 (5.9–32.4)

C: 12.5 (5.1 to 31.9)

I: 3.72 (±15.9)

C: 4.9 (±16)

INTERACT-2

I: 3.7 (2.8 to 4.8), h

C: 3.7 (2.9 to 4.7), h

I: 11 (6–19)

C: 11(6–20)

I: 3.1 (2.1–4.1)

C: 4.9 (3.1–6.6)

ATACH-2

I: 182.2 (57.2), min

C: 184.7 (56.7), min

I: 10.2 (2.3–85.2)

C: 10.2 (0.98–79.1)

I: n.a.

C: n.a.

  1. ICH Volume and Hematoma enlargement. a Time from onset to treatment.