From: Derivation and validation of a screening tool for stroke-associated sepsis
Organ system | S-SOFA score cutoff indicating a score of 1 | SOFA score cutoffs indicating a score of 1; 2; 3; 4, respectively |
---|---|---|
CNS | NIHSS ≥ 14 | GCS 13–14; 10–12; 6–9; <6 |
Respiration | SpO2 <90% | PaO2/FIO2, mmHg < 400; <300; <200; <100 |
Cardiovascular | MAP < 70 mmHg | MAP < 70 mmHg; vasopressor dosage, µg/kg/min dopamine ≤ 5 or dobutamine (any dose); dopamine 5–15, epinephrine/norepinephrine ≤ 0.1; dopamine > 15, epinephrine/norepinephrine > 0.1 |
Coagulation | Thrombocyte count < 150 109/l | Thrombocyte count, 109/l < 150; <100; <50; <20 |
Liver | - | Bilirubin, mg/dl 1.2–1.9; 2.0-5.9; 6.0-11.9; >12.0 |
Renal | Creatinine ≥ 1.2 mg/dl | Creatinine, mg/dl 1.2–1.9; 2.0-3.4; 3.5–4.9 or urine output < 500 ml/d; >5.0 or urine output < 200 ml/d |
Score range | 0–5 | 0–24 |
Relevant increase | ≥ 2 over baseline | ≥ 2 over baseline |