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Table 2 Comparison of S-SOFA and SOFA score parameters

From: Derivation and validation of a screening tool for stroke-associated sepsis

Organ system

S-SOFA score cutoff indicating a score of 1

SOFA score

cutoffs indicating a score of 1; 2; 3; 4, respectively

CNS

NIHSS ≥ 14

GCS 13–14; 10–12; 6–9; <6

Respiration

SpO2 <90%

PaO2/FIO2, mmHg < 400; <300; <200; <100

Cardiovascular

MAP < 70 mmHg

MAP < 70 mmHg; vasopressor dosage, µg/kg/min dopamine ≤ 5 or dobutamine (any dose); dopamine 5–15, epinephrine/norepinephrine ≤ 0.1; dopamine > 15, epinephrine/norepinephrine > 0.1

Coagulation

Thrombocyte count < 150 109/l

Thrombocyte count, 109/l < 150; <100; <50; <20

Liver

-

Bilirubin, mg/dl 1.2–1.9; 2.0-5.9; 6.0-11.9; >12.0

Renal

Creatinine ≥ 1.2 mg/dl

Creatinine, mg/dl 1.2–1.9; 2.0-3.4; 3.5–4.9 or urine output < 500 ml/d; >5.0 or urine output < 200 ml/d

Score range

0–5

0–24

Relevant increase

≥ 2 over baseline

≥ 2 over baseline

  1. Abbreviations: CNS = central nervous system, MAP = mean arterial pressure, SOFA = Sequential Organ Failure Assessement, S-SOFA = Stroke-SOFA