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Table 5 Dosage of important antibiotics used in acute bacterial meningitis in adults

From: German guidelines on community-acquired acute bacterial meningitis in adults

Antibiotic

Dosage per day

Penicillin G

6 × 5 Mio IE

Ampicillin

6 × 2 g

Cefotaxim

4 (bis 6) x 2 g

Ceftazidime

3 × 2 g

Ceftriaxone

1 × 4 oder 2 × 2 g

Meropenem

3 × 2 g

Fosfomycin

3 × 5 g2

Rifampicin

1 × 600 mg

Vancomycin

2 × 1 g1

Linezolid

2 × 600 mg

Gentamicin

1 × 240–360 mg3

Metronidazole

3 × 500 mg

  1. 1Determination of serum levels required. Cave: Dexamethasone might impair the penetration of vancomycin into the CSF [44]. 2Possibly, a fosfomycin-dosage of 3 × 8 g/d is needed to treat ventriculitis [45]. 3The daily gentamicin-dosis is 3–6 mg/kg KG. Determination of serum levels required
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Neurological Research and Practice

ISSN: 2524-3489

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