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Table 1 Clinical Characteristics of Cohort 1

From: Effects of body mass index on the immune response within the first days after major stroke in humans

Variable

Patient Group (N = 40)

Control Group (N = 16)

Age [Years, Mean ± SD]

71 ± 14

71 ± 8

Sex [as % female]

55%

44%

BMI [Mean ± SD]

28.45 ± 5.13

27.30 ± 3.42

First MRI Liver fat [%, Mean ± SD]

8.30% ± 2.76

13.18 ± 8.15

Second MRI Liver fat [%, Mean ± SD]

7.85% ± 2.40

NA$

Weight Categories

  

Obese [n (%)]

15 (37.5)

3 (18.8)

Overweight [n (%)]

14 (35.0)

9 (56.3)

Normal [n (%)]

11 (27.5)

6 (15.0)

Comorbidities

  

Hypertension [n (%)]

31 (77.5)

8 (50)

Diabetes mellitus [n (%)]

6 (15)

5 (31.9)

Stroke Characteristics

  

Etiology

  

Large-artery atherosclerosis

10 (25)

NA$

Cardioembolism [n (%)]

19 (47.5)

NA$

Stroke of other determined etiology [n (%)]

2 (5)

NA$

Stroke of undetermined etiology [n (%)]

9 (22.5)

NA$

First MRI Stroke Size [ml3, Median (IQR)]

31.0 (7.5–78.0)

NA$

Second MRI Stroke Size [ml3, Median (IQR)]

41.2 (8.2–89.6)

NA$

Initial NIHSS score [Median (IQR)]

15 (11.25-21.00)

NA$

Infarct size [n (%), left-sided infarcts]

20 (50.0)

NA$

Treatment [n (%)]

30 (75.0)

NA$

Systemic thrombolysis [n (%)]&

25 (62.5)

NA$

Mechanical thrombectomy [n (%)]&

18 (45.0)

NA$

Combined treatment [n (%)]

13 (32.5)

NA$

  1. For the analysis of soluble mediators (cytokines, chemokines, and adipokines,) as well as adaptive immune cell subpopulations 40 stroke patients and 16 control patients were analyzed on the day of admission and on days 1, 2, 3, 4, 5 and 7 thereafter. Patients were enrolled from 2015-2016.