Table 2 Predictors for a favorable outcome at telephone interview assessed by dichotomized mRS (mRS = 0 or 1 versus greater than or equal to 2) (N = 228)

Age

67.9 ± 11.7

77.5 ± 10.6

U = 9,461.000, Z = 6.032, p < 0.001^c

Sex-Female

44/122 (36.1%)

52/106 (49.1%)

3.927/0.048^a

Aetiology of stroke

Large artery atherosclerosis stroke (LAAS)

14 (11.5%)

7 (6.7%)

4.531/0.997^a

Cardioembolic stroke (CES)

28 (23.0%)

28 (26.7%)

Cerebral small-vessel disease (SVD)

23 (18.9%)

21 (20.0%)

Cryptogenic stroke

57 (46.7%)

49 (46.7%)

Event to door time

≤ 2 h

78/122 (63.9%)

50/106 (47.2%)

6.474/0.008^a

Door to needle time

45.1 ± 25.2 min

46.6 ± 24.4 min

U = 6,847.000, Z = 0.767, p = 0.443^c

(Median 37)

(Median 40.5)

Severity indices on admission

Modified Rankin Scale on admission

2.8 ± 0.9

3.4 ± 0.9

U = 8,269.000, Z = 3.865, p < 0.001^c

Median: 3

Median: 3

Modified Rankin Scale on admission

Score 0: 1 (0.8%)

Score 0: 0 (0%)

19.425/< 0.001^a

Score 1: 4 (3.3%)

Score 1: 0 (0%)

Score 2: 38 (31.1%)

Score 2: 17 (16.0%)

Score 3: 54 (44.3%)

Score 3: 51 (48.1%)

Score 4: 20 (16.4%)

Score 4: 20 (18.9%)

Score 5: 5 (4.1%)

Score 5: 18 (17.0%)

NIHSS on admission

4.9 ± 4.0

7.8 ± 7.1

U = 8,353.000, Z = 3.817, p < 0.001^c

Median: 4

Median: 5.5

NIHSS after 24 h

1.7 ± 2.6

5.1 ± 5.8

U = 9,547.000, Z = 6.822, p < 0.001^c

Median: 1

Median: 3

Risk factors

Hypertension

102/122 (83.6%)

101/106 (95.3%)

7.921/0.005^a

Systolic blood pressure on admission

165.7 ± 25.7 mm Hg

168.2 ± 29.8 mm Hg

U = 6,586.500, Z = 0.495, p = 0.621^c

Diastolic blood pressure on admission

90.8 ± 15.7 mm Hg

88.2 ± 15.1 mm Hg

U = 5,752.000, Z = 1.209, p = 0.227^c

Diabetes mellitus

18/122 (14.8%)

22/106 (20.8%)

1.412/0.235^a

Blood glucose level on admission

133.9 ± 55.6 mg/dl

135.0 ± 43.7 mg/dl

U = 6,957.000, Z = 1.102, p = 0.270^c

HbA1c

41.7 ± 12.9 mmol/mol

42.8 ± 11.1 mmol/mol

U = 6,902.500, Z = 1.622, p = 0.105^c

Cholesterol level on admission

203.0 ± 42.7 mg/dl

188.7 ± 47.7 mg/dl

U = 5,207.500, Z = 2.135, p = 0.033^c

LDL level on admission

129.5 ± 37.9 mg/dl

118.5 ± 41.6 mg/dl

U = 5,273.000, Z = 1.888, p = 0.059^c

Statine therapy on admission

36/121 (29.8%)

41/106 (38.7%)

2.009/0.156^a

CRP level on admission

3.3 ± 5.8 mg/dl

10.8 ± 31.6 mg/dl

U = 7,230.500, Z = 1.657, p = 0.098^c

Atrial fibrillation

19/122 (15.6%)

23/106 (21.7%)

1.416/0.234^a

Former stroke

14/122 (11.5%)

33/106 (31.1%)

13.392/< 0.001^a

Antiaggregant therapy on admission

31/121 (25.6%)

51/106 (48.1%)

12.389/< 0.001^a

Complications

Intracerebral bleeding

3/122 (2.5%)

7/106 (6.6.%)

3.529/0.317^a

Seizure

2/122 (1.6%)

1/106 (0.9%)

0.212/0.646^a

Recurrent stroke/TIA within 72 h

1/122 (0.8%)

1/106 (0.9%)

0.010/0.920^a

Infection within 72 h

15/122 (12.3%)

21/106 (19.8%)

2.410/0.121^a

Delirium

3/122 (2.5%)

9/106 (8.5%)

4.138/0.042^a

Pre-stroke living situation

German level of care (0–5)

0: 119 (97.5%)

0: 61 (73.5%)

27.575/< 0.001^a

1: 1 (0.8%)

1: 2 (2.4%)

2: 1 (0.8%)

2: 12 (14.5%)

3: 1 (0.8%)

3: 5 (6.0%)

4: 0 (0%)

4: 3 (3.6%)

5: 0 (0%)

5: 0 (0%)