Table 3 Predictors for a favorable outcome at telephone interview assessed by dichotomized EQ index of the EQ-5D-5L (EQ index ≥ 0.970 versus EQ index < 0.970) (N = 206)

Age

65.6 ± 11.4

74.7 ± 10.4

U = 2,778.500, Z = 5.546, p < 0.001^c

Sex-Female

25/83 (30.1%)

56/123 (45.5%)

4.931/0.026^a

Aetiology of stroke

LAAS

9 (10.8%)

12 (9.8%)

2.482/0.779^a

CES

22 (26.5%)

29 (23.8%)

SVD

15 (18.1%)

22 (18.0%)

Other

1 (1.2%)

1 (0.8%)

Cryptogenic stroke

15 (18.1%)

33 (27.0%)

ESUS

21 (25.3%)

25 (20.5%)

Event to door time

≤ 2 h

48/83 (57.8%)

70/123 (56.9%)

0.017/0.896^a

Door to needle time

43.4 ± 26.1 min

44.5 ± 20.5 min

U = 4,574.500, Z = 1.263, p = 0.206^c

(Median 36)

(Median 38)

Severity indices on admission

Modified Rankin Scale on admission

2.9 ± 1.0

3.1 ± 0.9

U = 4,359.000, Z = 1.898, p = 0.058^c

Median: 3

Median: 3

Modified Rankin Scale on admission

Score 0: 0 (0%)

Score 0: 1 (0.8%)

7.859/0.164^a

Score 1: 3 (3.6%)

Score 1: 1 (0.8%)

Score 2: 28 (33.7%)

Score 2: 25 (20.3%)

Score 3: 33 (39.8%)

Score 3: 63 (51.2%)

Score 4: 13 (15.7%)

Score 4: 22 (17.9%)

Score 5: 6 (7.2%)

Score 5: 11 (8.9%)

NIHSS on admission

5.3 ± 4.3

6.0 ± 5.2

U = 4,678.000, Z = 1.022, p = 0.307^c

Median: 4

Median: 5

NIHSS after 24 h

1.8 ± 2.7

3.5 ± 4.8

U = 3,815.500, Z = 2.972, p = 0.003^c

Median: 1

Median: 2

Risk factors

Hypertension

69/83 (83.1%)

112/123 (91.1%)

2.919/0.088^a

Systolic blood pressure on admission

166.1 ± 25.1 mm Hg

167.1 ± 28.2 mm Hg

T = 0.259, p = 0.796^b

Diastolic blood pressure on admission

91.8 ± 16.7 mm Hg

88.3 ± 14.8 mm Hg

U = 5,810.000, Z = 1.956, p = 0.050^c

Diabetes mellitus

10/83 (12.0%)

26/123 (21.1%)

2.839/0.092^a

Blood glucose level on admission

132.6 ± 51.0 mg/dl

136.5 ± 51.2 mg/dl

U = 4,687.500, Z = 0.854, p = 0.393^c

HbA1c

40.9 ± 13.0 mmol/mol

42.6 ± 10.7 mmol/mol

U = 3,819.000, Z = 2.574, p = 0.010^c

Cholesterol level on admission

204.8 ± 42.3 mg/dl

192.7 ± 46.1 mg/dl

T = 1.895, p = 0.060^b

LDL level on admission

131.8 ± 35.3 mg/dl

120.6 ± 40.8 mg/dl

U = 5,754.500, Z = 2.097, p = 0.036^c

Statine therapy on admission

21/82 (25.6%)

49/123 (39.8%)

4.429/0.035^a

CRP level on admission

3.0 ± 5.1 mg/dl

9.1 ± 29.2 mg/dl

U = 4,225.000, Z = 1.967, p = 0.049^c

Atrial fibrillation

11/83 (13.3%)

25/123 (20.3%)

1.719/0.190^a

Former stroke

9/83 (10.8%)

29/123 (23.6%)

5.342/0.021^a

Antiaggregant therapy on admission

21/83 (25.3%)

53/122 (43.4%)

7.047/0.008^a

Complications

Intracerebral bleeding

2/83 (2.4%)

6/123 (4.9.%)

1.155/0.764^a

Seizure

1/83 (1.2%)

2/123 (1.6%)

0.061/0.805^a

Recurrent stroke/TIA within 72 h

0/83 (0%)

2/123 (1.6%)

1.363/0.243^a

Infection within 72 h

7/83 (8.4%)

22/123 (17.9%)

3.661/0.056^a

Delirium

3/83 (3.6%)

7/123 (5.7%)

0.463/0.496^a

Pre-stroke living situation

German level of care (0–5)

0: 83 (100%)

0: 97 (79.5%)

19.370/< 0.001^a

1: 0 (0%)

1: 3 (2.5%)

2: 0 (0%)

2: 13 (10.7%)

3: 0 (0%)

3: 6 (4.9%)

4: 0 (0%)

4: 3 (2.5%)

5: 0 (0%)

5: 0 (0%)

MRI parameters