Table 4 Predictors for a favorable outcome at telephone interview assessed by dichotomized EQ VAS of the EQ-5D-5L (EQ VAS ≥ 75 versus EQ VAS < 75) (N = 206)

Age

68.0 ± 12.0

73.1 ± 11.1

U = 3,875.000, Z = 2.972, p = 0.003^c

Sex-female

27/84 (32.1%)

54/122 (44.3%)

3.063/0.080^a

Aetiology of stroke

LAAS

9 (10.8%)

12 (9.8%)

0.817/0.976^a

CES

21 (25.3%)

30 (24.6%)

SVD

15 (18.1%)

22 (18.0%)

Other

1 (1.2%)

1 (0.8%)

Cryptogenic stroke

17 (20.5%)

31 (25.4%)

ESUS

20 (24.1%)

26 (21.3%)

Event to door time

≤ 2 h

54/84 (64.3%)

64/122 (52.5%)

2.844/0.092^a

Door to needle time

44.8 ± 26.0 min

43.6 ± 20.6 min

U = 5,000.000, Z = 0.295, p = 0.768^c

(Median 37)

(Median 38)

Severity indices on admission

Modified Rankin Scale on admission

2.8 ± 0.9

3.2 ± 0.9

U = 4,170.000, Z = 2.424, p = 0.015^c

Median: 3

Median: 3

Modified Rankin Scale on admission

Score 0: 0 (0%)

Score 0: 1 (0.8%)

11.479/0.043^a

Score 1: 4 (4.8%)

Score 1: 0 (0%)

Score 2: 27 (32.1%)

Score 2: 26 (21.3%)

Score 3: 36 (42.9%)

Score 3: 60 (49.2%)

Score 4: 13 (15.5%)

Score 4: 22 (18.0%)

Score 5: 4 (4.8%)

Score 5: 13 (10.7%)

NIHSS on admission

5.2 ± 4.4

6.1 ± 5.1

U = 4,411.500, Z = 1.704, p = 0.088^c

Median: 4

Median: 5

NIHSS after 24 h

1.8 ± 2.8

3.6 ± 4.8

U = 3,595.500, Z = 3.553, p < 0.001^c

Median: 1

Median: 2

Risk factors

Hypertension

66/84 (78.6%)

115/122 (94.3%)

11.486/< 0.001^a

Systolic blood pressure on admission

167.0 ± 28.3 mm Hg

166.3 ± 25.0 mm Hg

T = 0.173, p = 0.863^b

Diastolic blood pressure on admission

89.3 ± 15.3 mm Hg

90.0 ± 15.9 mm Hg

U = 4,882.000, Z = 0.337, p = 0.736^c

Diabetes mellitus

12/84 (14.3%)

24/122 (19.7%)

1.001/0.317^a

Blood glucose level on admission

136.5 ± 53.8 mg/dl

133.9 ± 49.2 mg/dl

U = 5,215.000, Z = 0.365, p = 0.715^c

HbA1c

41.8 ± 13.4 mmol/mol

42.0 ± 10.4 mmol/mol

U = 4,570.500, Z = 0.804, p = 0.421^c

Cholesterol level on admission

201.2 ± 44.1 mg/dl

194.9 ± 45.3 mg/dl

U = 5,382.500, Z = 0.978, p = 0.328^c

LDL level on admission

126.0 ± 38.3 mg/dl

124.5 ± 39.7 mg/dl

U = 5,057.500, Z = 0.291, p = 0.771^c

Statine therapy on admission

23/83 (32.9%)

47/122 (38.5%)

2.569/0.109^a

CRP level on admission

2.7 ± 5.0 mg/dl

9.3 ± 29.3 mg/dl

U = 3,679.000, Z = 3.322, p < 0.001^c

Atrial fibrillation

12/84 (14.3%)

24/122 (19.7%)

1.001/0.317^a

Former stroke

14/84 (16.7%)

24/122 (19.7%)

0.299/0.585^a

Antiaggregant therapy on admission

19/82 (23.2%)

55/123 (44.7%)

9.900/0.002^a

Complications

Intracerebral bleeding

2/84 (2.4%)

6/122 (4.9.%)

1.203/0.752^a

Seizure

1/84 (1.2%)

2/122 (1.6%)

0.070/0.792^a

Recurrent stroke/TIA within 72 h

0/84 (0%)

2/122 (1.6%)

1.391/0.238^a

Infection within 72 h

11/84 (13.1%)

18/122 (14.8%)

0.113/0.737^a

Delirium

3/84 (3.6%)

7/122 (5.7%)

0.505/0.477^a

Pre-stroke living situation

German level of care (0–5)

0: 80 (95.2%)

0: 100 (82.6%)

8.249/0.083^a

1: 0 (0%)

1: 3 (2.5%)

2: 3 (3.6%)

2: 10 (8.3%)

3: 1 (1.2%)

3: 5 (4.1%)

4: 0 (0%)

4: 3 (2.5%)

5: 0 (0%)

5: 0 (0%)