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Fig. 3 | Neurological Research and Practice

Fig. 3

From: Preoperative motor deficits and depressive symptoms predict quality of life in patients with Parkinson’s disease at different time points after surgery for subthalamic stimulation: a retrospective study

Fig. 3

– Prediction of the PDQ-39 change scores at 12 months follow-up by pre-operative baseline parameters. Change scores in the PDQ-39 total score were predicted by the HADS depression (β = 0.52, p = 0.007), accounting for 11% of the variance [F(1,61) = 7.82, p = 0.007]. Change scores in the PDQ-39 subscale stigma were predicted by the HADS depression (β = 0.73, p = 0.014), explaining 10% of the variance [F(1,61) = 6.42, p = 0.014]. Change scores in the PDQ-39 subscale communication were predicted by the HADS depression (β = 0.77, p = 0.019), accounting for 9% the variance each [F(1,61) = 5.76, p = 0.019]. Change scores in the PDQ-39 subscale emotional well-being were predicted by the HADS depression (β = 0.74, p = 0.015), explaining 9% of the variance [F(1,61) = 6.33, p = 0.015]. Change scores in the PDQ-39 subscale social support were predicted by the UPDRS-III total score (β = 0.26, p = 0.037), explaining 7% of the variance [F(1,61) = 4.56, p = 0.037]. For clarity, only significant predictors from the final regression model are displayed. Each colour of the arrows represents a separate multiple linear regression. HADS Hospital Anxiety and Depression Scale, MoCA Montreal Cognitive Assessment, PANDA Parkinson’s Neuropsychometric Dementia Assessment, PDQ-39 Parkinson’s Disease Questionnaire 39, R2 bias corrected regression coefficient R2, UPDRS-III Unified Parkinson’s Disease Rating Scale Part III, UPDRS-III PIGD postural instability and gait disorder subscore of the Unified Parkinson’s Disease Rating Scale Part III

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