Table 2 Patient characteristics, status epilepticus characteristics, and outcomes stratified by tumor categories and tumor progression signs

All cases

208 (100)

116 (55.8)

30 (14.4)

53 (25.5)

128 (61.5)

80 (38.5)

Patient Characteristics

Age at SE onset (years)

 Mean ± SD

61.5 ± 14.7

59.1 ± 15.4

70.8 ± 12.8

60.9 ± 11.6

& < 0.001; #0.003; §n.s

61.4 ± 15.4

61.5 ± 13.6

n.s

 Median (Range)

62.5 (23–89)

60.5 (23–88)

72.5 (33–89)

62 (31–96)

63.5 (23–89)

61 (31–88)

Sex

 Male

106 (51)

72 (62)

7 (23.3)

22 (41.5)

& < 0.001; #0.046; §0.009

66 (51.6)

40 (50)

n.s

Charlson comorbidity Index (CCI)

 2–5

145 (69.7)

110 (94.8)

26 (86.7)

0

&n.s.; # < 0.001; § < 0.001

81 (63.3)

64 (80)

0.008

 > 6

63 (30.3)

6 (5.2)

4 (13.3)

53(100)

47 (36.7)

16 (20)

Previous history of seizures

 Yes

127 (61.1)

83 (71.6)

17 (56.7)

23 (43.4)

&0.045; #n.s.; § < 0.001

69 (53.9)

58 (72.5)

0.007

Previous history of SE

 Yes

22 (10.6)

14 (12)

5 (16.7)

3 (5.7)

n.s

12 (9.4)

10 (12.5)

n.s

mRS before admission

 0–2

118 (56.7)

66 (56.9)

18 (60)

27 (50.9)

n.s

69 (53.9)

49 (61.3)

n.s

 3–5

90 (43.3)

50 (43.1)

12 (40)

26 (49.1)

59 (46.1)

31 (38.8)

SE Characteristics

STESS

 0–3

176 (84.6)

104 (89.7)

18 (60)

46 (86.8)

& < 0.001; #0.002; §n.s

110 (85.9)

66 (82.5)

n.s

 4–6

32 (15.4)

12 (10.3)

12 (40)

7 (13.2)

18 (14.1)

14 (17.5)

Refractoriness of SE

 NRSE

95 (45.7)

57 (49.1)

10 (33.3)

24 (45.3)

n.s. **

56 (43.8)

39 (48.8)

n.s.**

 RSE

94 (45.2)

50 (43.1)

15 (50)

25 (47.2)

61 (47.7)

33 (41.3)

 SRSE

19 (9.1)

9 (0.8)

5 (16.7)

4 (7.5)

11 (8.6)

8 (10)

Tumor progression signs

 Yes

128 (61.5)

71 (61.2)

9 (30)

41 (77.4)

& < 0.001; # < 0.001; §0.05

128 (100)

0

n.t

Tumor diagnosed at admission

 Yes

57 (27.4)

22 (19)

8 (26.7)

23 (43.4)

&n.s.; #n.s.; §0.001

53 (41.4)

4 (5)

 < 0.001

Time between tumor diagnosis and SE onset (years)

 Mean ± SD

2.3 ± 4.4

2.3 ± 4.1

5.3 ± 7.1

0.6 ± 0.9

&0.003; #0.002; §n.s

1.7 ± 4.0

3.2 ± 4.9

 < 0.001

 Median (Range)

0.5 (0–24.5)

0.6 (0–24.5)

2.1 (0–21.2)

0.2 (0–4.5)

0.3 (0–24.5)

1.2 (0–21.2)

Outcome

mRS at discharge

 0–2

61 (29.4)

36 (31)

8 (26.7)

14 (26.4)

n.s

28 (21.9)

33 (41.3)

0.003

 3–6

147 (70.7)

80 (69)

22 (73.3)

39 (73.6)

100 (78.1)

47 (58.8)

Discharge destination

 Home

79 (38.0)

49 (42.2)

7 (23.3)

19 (35.8)

46 (36)

33 (41.3)

 Rehabilitation

39 (18.8)

21 (18.1)

14 (46.7)

4 (7.5)

16 (12.5)

23 (28.8)

 Other hospital

21 (10.1)

9 (7.8)

3 (10)

7 (13.2)

12 (9.4)

9 (11.3)

 Nursing home

9 (4.3)

5 (4.3)

1 (3.3)

3 (5.7)

6 (4.7)

3 (3.8)

 Palliative Care/Hospice

15 (7.2)

10 (8.6)

0

4 (7.5)

12 (9.4)

3 (3.8)

 Other

9 (4.3)

7 (6)

0

2 (3.8)

4 (3.1)

5 (6.3)

Mortality

 In-hospital

36 (17.3)

15 (13)

5 (16.7)

14 (26.4)

&n.s.; #n.s.; §0.031 ***

32 (25)

4 (5)

 < 0.001 ***

 30 days

50 (24.0)

26 (22.4)

5 (16.7)

17 (32.1)

n.s

41 (32)

9 (11.2)

0.001 ***

 1 year

137 (65.9)

79 (68.1)

11 (36.7)

42 (79.2)

&0.003; # < 0.001; §n.s. ***

98 (76.5)

39 (48.8)

 < 0.001 ***