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  1. Results of randomized controlled trials (RCT) do not provide definite guidance for secondary prevention after ischemic stroke (IS)/transient ischemic attack (TIA) attributed to patent foramen ovale (PFO). No r...

    Authors: Sven Poli, Elisabeth Siebert, Joshua Mbroh, Khouloud Poli, Markus Krumbholz, Annerose Mengel, Simon Greulich, Florian Härtig, Karin A. L. Müller, Wolfgang Bocksch, Meinrad Gawaz, Ulf Ziemann and Christine S. Zuern
    Citation: Neurological Research and Practice 2021 3:16
    Content type: Research article Published on:

  2. COVID-19 pandemic caused a decline in stroke care in several countries. The objective was to describe lockdown stroke care in a tertiary stroke center in Düsseldorf, Germany near Heinsberg, a German hot spot f...

    Authors: Robin Jansen, John-Ih Lee, Bernd Turowski, Marius Kaschner, Julian Caspers, Michael Bernhard, Hans-Peter Hartung, Sebastian Jander, Tobias Ruck, Sven G. Meuth and Michael Gliem
    Citation: Neurological Research and Practice 2021 3:21
    Content type: Research article Published on:

  3. Since the outbreak of coronavirus disease 2019 (COVID-19), a growing number of cases of acute transverse myelitis associated with COVID-19 have been reported. Here, we present the case of a patient who develop...

    Authors: Ji-Won Kim, Nuran Abdullayev, Janina Neuneier, Gereon R. Fink and Helmar C. Lehmann
    Citation: Neurological Research and Practice 2021 3:18
    Content type: Letter to the editor Published on:

  4. The SARS-Coronavirus-2 (SARS-CoV-2) invades the respiratory system, causing acute and sometimes severe pulmonary symptoms, but turned out to also act multisystematically with substantial impact on the brain. A...

    Authors: Ummehan Ermis, Marcus Immanuel Rust, Julia Bungenberg, Ana Costa, Michael Dreher, Paul Balfanz, Gernot Marx, Martin Wiesmann, Kathrin Reetz, Simone C. Tauber and Jörg B. Schulz
    Citation: Neurological Research and Practice 2021 3:17
    Content type: Research article Published on:

  5. Insomnia is defined as difficulties of initiating and maintaining sleep, early awakening and poor subjective sleep quality despite adequate opportunity and circumstances for sleep with impairment of daytime pe...

    Authors: Geert Mayer, Svenja Happe, Stefan Evers, Wiebke Hermann, Sabine Jansen, Ulf Kallweit, Maria-Lucia Muntean, Dieter Pöhlau, Dieter Riemann, Michael Saletu, Melanie Schichl, Wolfgang J. Schmitt, Friederike Sixel-Döring and Peter Young
    Citation: Neurological Research and Practice 2021 3:15
    Content type: Guidelines Published on:

  6. Delirium is a frequent complication in hospitalised patients, often leading to difficulties in patient management and is associated with increased morbidity and mortality. Most patients in intensive care units...

    Authors: Juraj Kukolja and Jens Kuhn
    Citation: Neurological Research and Practice 2021 3:12
    Content type: Standard operating procedure Published on:

  7. Computed tomography angiography (CTA) of the head and neck during acute ischemic stroke (AIS) usually includes visualization of lung apices. The possibility to evaluate for pulmonary changes, e.g. peripheral g...

    Authors: Johannes A. R. Pfaff, Bianka Füssel, Marcial E. Harlan, Alexander Hubert and Martin Bendszus
    Citation: Neurological Research and Practice 2021 3:10
    Content type: Research article Published on:

  8. Vestibular schwannomas (VS) are benign slow growing tumors arising from the vestibular nerve. The role of cyclooxygenase 2 (COX2) in tumor development of growth has been addressed in a few studies with contrad...

    Authors: Felix Behling, Elisa Suhm, Vanessa Ries, Vítor Moura Gonçalves, Ghazaleh Tabatabai, Marcos Tatagiba and Jens Schittenhelm
    Citation: Neurological Research and Practice 2021 3:11
    Content type: Research article Published on:

  9. Direct oral anticoagulants (DOAC) including edoxaban are increasingly used for stroke prevention in atrial fibrillation. Despite treatment, annual stroke rate in these patients remains 1–2%. Rapid assessment o...

    Authors: Florian Härtig, Ingvild Birschmann, Andreas Peter, Sebastian Hörber, Matthias Ebner, Matthias Sonnleitner, Charlotte Spencer, Paula Bombach, Maria-Ioanna Stefanou, Johannes Tünnerhoff, Annerose Mengel, Joachim Kuhn, Ulf Ziemann and Sven Poli
    Citation: Neurological Research and Practice 2021 3:9
    Content type: Research article Published on:

  10. Up to 2/3rd of the stroke subjects may experience impairment in any of the somatosensory modalities such as light touch, proprioception, and stereognosis. The sensory recovery is strongly associated with the l...

    Authors: Kamal Narayan Arya, Shanta Pandian, G. G. Agarwal, Neera Chaudhary and Akshay Kumar Joshi
    Citation: Neurological Research and Practice 2021 3:8
    Content type: Clinical trial protocol Published on:

  11. Stroke has a long-term impact on functional status and quality of life in multiple health domains. A well-coordinated managed care program for stroke patients is crucial for ameliorating patients’ health and c...

    Authors: David Leander Rimmele, Theresa Schrage, Christian Brettschneider, Alexander Engels, Christian Gerloff, Martin Härter, Michael Rosenkranz, Holger Schmidt, Levente Kriston and Götz Thomalla
    Citation: Neurological Research and Practice 2021 3:7
    Content type: Clinical trial protocol Published on:

  12. Medical progress, economization of healthcare systems, and scarcity of resources raise fundamental ethical issues. Physicians are exposed to increasing moral conflict situations, which may cause Moral Distress...

    Authors: Hanna Hildesheim, Annette Rogge, Christoph Borzikowsky, Victoria Dorothea Witt, Eva Schäffer and Daniela Berg
    Citation: Neurological Research and Practice 2021 3:6
    Content type: Research article Published on:

  14. Safety data of intravenous thrombolysis (IVT) in presence of aortic arch thrombus is scant. Furthermore, IVT is debatable in patients with prior recent stroke. We present a 51-year-old woman with recurrent maj...

    Authors: Ioanna Koutroulou, Georgios Tsivgoulis, Vasileios Rafailidis, Elissavet Psoma, Konstantinos Kouskouras, Panagiotis Fotiadis, Nikolaos Grigoriadis and Theodoros Karapanayiotides
    Citation: Neurological Research and Practice 2021 3:4
    Content type: Letter to the editor Published on:

  16. Despite antibiotic therapy, adjunctive treatment with dexamethasone, and care on modern intensive care units, bacterial meningitis remains a life-threatening disease with a high mortality and morbidity. One of...

    Authors: Susanne Dyckhoff-Shen, Uwe Koedel, Hans-Walter Pfister and Matthias Klein
    Citation: Neurological Research and Practice 2021 3:2
    Content type: Standard operating procedure Published on:

  17. Routing of patients with intracerebral hemorrhage (ICH) and acute ischemic stroke (AIS) to the most appropriate hospital is challenging for emergency medical services particularly when specific treatment optio...

    Authors: Frederik Geisler, Medschid Wesirow, Martin Ebinger, Alexander Kunz, Michal Rozanski, Carolin Waldschmidt, Joachim E. Weber, Matthias Wendt, Benjamin Winter and Heinrich J. Audebert
    Citation: Neurological Research and Practice 2021 3:1
    Content type: Research article Published on:

  18. Epileptic seizures are common clinical features in patients with acute subdural hematoma (aSDH); however, diagnostic feasibility and therapeutic monitoring remain limited. Surface electroencephalography (EEG) ...

    Authors: Sae-Yeon Won, Thomas M. Freiman, Philipp S. Reif, Daniel Dubinski, Elke Hattingen, Eva Herrmann, Volker Seifert, Felix Rosenow, Adam Strzelczyk and Juergen Konczalla
    Citation: Neurological Research and Practice 2020 2:50
    Content type: Clinical trial protocol Published on:

  19. Traumatic and non-traumatic spinal cord injury bears a high risk for thromboembolism in the first few months after injury. So far, there is no consented guideline regarding diagnostic and prophylactic measures...

    Authors: Norbert Weidner, Oliver J. Müller, Viola Hach-Wunderle, Karsten Schwerdtfeger, Rüdiger Krauspe, Rolf Pauschert, Christian Waydhas, Michael Baumberger, Christoph Göggelmann, Gabriela Wittgruber, Renate Wildburger and Oswald Marcus
    Citation: Neurological Research and Practice 2020 2:43
    Content type: Guidelines Published on:

  20. Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the...

    Authors: Maike F. Dohrn, Ulrike Schöne, Charlotte Küppers, Deborah Christen, Jörg B. Schulz, Burkhard Gess and Simone Tauber
    Citation: Neurological Research and Practice 2020 2:52
    Content type: Letter to the editor Published on:

  21. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common chronic inflammatory neuropathy. CIDP is diagnosed according to the European Federation of Neurological Societies/Peripheral ...

    Authors: Anna Lena Fisse, Jeremias Motte, Thomas Grüter, Melissa Sgodzai, Kalliopi Pitarokoili and Ralf Gold
    Citation: Neurological Research and Practice 2020 2:42
    Content type: Review Published on:

  22. Diagnosis of functional movement disorders and specifically functional tremor (FT) (representing 50% of them) remains demanding. Additionally, due to heterogeneity of the disorders, structured concepts and gui...

    Authors: Michael Bartl, Rebekka Kewitsch, Mark Hallett, Martin Tegenthoff and Walter Paulus
    Citation: Neurological Research and Practice 2020 2:35
    Content type: Review Published on:

  23. Infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to a previously unknown clinical picture, which is known as COVID-19 (COrona VIrus Disease-2019) and was first describe...

    Authors: Peter Berlit, Julian Bösel, Georg Gahn, Stefan Isenmann, Sven G. Meuth, Christian H. Nolte, Marc Pawlitzki, Felix Rosenow, Benedikt Schoser, Götz Thomalla and Thomas Hummel
    Citation: Neurological Research and Practice 2020 2:51
    Content type: Guidelines Published on:

  24. There is no shortage of books, chapters and papers on the history of stroke focusing predominantly on the last 150 years and enumerating endless “milestones”. Instead of adding another article to this body of ...

    Authors: Axel Karenberg
    Citation: Neurological Research and Practice 2020 2:34
    Content type: Review Published on:

  25. Sphingosin-1-phosphate (S1P) plays a crucial role as a signaling molecule in the immune system and the vasculature. Previous studies suggested a role as a vasoconstrictor of cerebral arteries via the S1P3-Rece...

    Authors: Anika Männer, Dominique Thomas, Marlies Wagner, Jürgen Konczalla, Helmuth Steinmetz, Robert Brunkhorst and Waltraud Pfeilschifter
    Citation: Neurological Research and Practice 2020 2:49
    Content type: Research article Published on:

  26. The Coronavirus Disease 2019 (COVID-19) pandemic may have altered emergency workflows established to optimize the outcome of patients with large-vessel occlusion (LVO) stroke.

    Authors: Steffen Tiedt, Felix J. Bode, Timo Uphaus, Anna Alegiani, Klaus Gröschel and Gabor C. Petzold
    Citation: Neurological Research and Practice 2020 2:44
    Content type: Research article Published on:

  27. One quarter to one third of patients eligible for systemic thrombolysis are on antiplatelet therapy at presentation. In this study, we aimed to assess the safety and efficacy of intravenous thrombolysis in str...

    Authors: Benedikt M. Frey, Florent Boutitie, Bastian Cheng, Tae-Hee Cho, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Ian Ford, Ivana Galinovic, Alina Königsberg, Josep Puig, Pascal Roy, Anke Wouters, Tim Magnus, Vincent Thijs…
    Citation: Neurological Research and Practice 2020 2:40
    Content type: Research article Published on:

  28. Comparing health care parameters of acute ischemic stroke (AIS) patients with and without concurrent coronavirus disease 2019 (Covid-19, SARS-CoV-2 infection), may be helpful in terms of optimizing clinical an...

    Authors: Daniel Richter, Christos Krogias, Jens Eyding, Dirk Bartig, Armin Grau and Ralph Weber
    Citation: Neurological Research and Practice 2020 2:48
    Content type: Letter to the editor Published on:

  29. In view of the importance of neurosyphilis and the difficulties encountered in diagnosing it, the S1 guideline “Neurosyphilis” has been published by the German Society for Neurology (DGN) in accordance with th...

    Authors: Matthias Klein, Klemens Angstwurm, Stefan Esser, Kathrin Hahn, Matthias Maschke, Simone Scheithauer, Helmut Schoefer, Matthias Sturzenegger, Brigitte Wildemann and Jörg Weber
    Citation: Neurological Research and Practice 2020 2:33
    Content type: Guidelines Published on:

  30. Investigating clinical characteristics of patients presenting with cerebrovascular events during the pandemic may provide valuable insight into further understanding the phenomenon of decreased stroke admissio...

    Authors: Carolin Hoyer, Lenja Weber, Vesile Sandikci, Anne Ebert, Michael Platten and Kristina Szabo
    Citation: Neurological Research and Practice 2020 2:47
    Content type: Letter to the editor Published on:

  31. At present, “severe acute respiratory syndrome new coronavirus” (SARS-CoV-2) affects the whole world and has led to a pandemia with almost 2.000.000 infected patients in the mid of April 2020 (WHO). Thus, heal...

    Authors: Christian Urbanek, Jana Kötteritzsch, Wolfgang Zink and Armin J. Grau
    Citation: Neurological Research and Practice 2020 2:32
    Content type: Research article Published on:

  32. The presence of motor signs and symptoms in Parkinson’s disease (PD) is the result of a long-lasting prodromal phase with an advancing neurodegenerative process. The identification of PD patients in an early p...

    Authors: Jannik Prasuhn, Marcus Heldmann, Thomas F. Münte and Norbert Brüggemann
    Citation: Neurological Research and Practice 2020 2:46
    Content type: Research article Published on:

  33. “Printed by Parkinson’s” is an innovative project with the main aim to raise awareness for the many aspects of Parkinson’s disease and their implication for everyday life. In a cooperation of Innocean Worldwid...

    Authors: Lucia K. Feldmann and Andrea A. Kühn
    Citation: Neurological Research and Practice 2020 2:37
    Content type: Letter to the editor Published on:

  34. The advent of therapeutic strategies designed to modify the disease course in Parkinson’s disease has raised great expectations in the currently conducted clinical trials. However, we see ethical challenges in...

    Authors: D. Berg, K. Eggert, B. Haslinger, J. Kassubek, B. Mollenhauer, K. Reetz, A. Rogge, E. Schaeffer, L. Tönges and K. E. Zeuner
    Citation: Neurological Research and Practice 2020 2:31
    Content type: Position statement Published on:

  35. Recently different subtypes of myasthenia gravis (MG) have been described. They differ for clinical features and pathogenesis but the prognosis and response to treatment is less clear. The aim of the study was...

    Authors: Francesca Pasqualin, Silvia V. Guidoni, Mario Ermani, Elena Pegoraro and Domenico M. Bonifati
    Citation: Neurological Research and Practice 2020 2:45
    Content type: Research article Published on:

  36. Dementia in Parkinson’s disease (PDD) is a common non-motor symptom of advanced disease, associated with pronounced neocortical cholinergic deficits due to neurodegeneration of the nucleus basalis of Meynert (...

    Authors: Christine Daniels, Frank Steigerwald, Philipp Capetian, Cordula Matthies, Uwe Malzahn, Peter U. Heuschmann and Jens Volkmann
    Citation: Neurological Research and Practice 2020 2:41
    Content type: Clinical trial protocol Published on:

  37. Nowadays B-cell depletion via anti-CD20 antibodies is commonly applied in the treatment of multiple sclerosis (MS). Yet, not much is known about infection risks associated with long-term B-cell depletion in th...

    Authors: Carolin Schwake and Ralf Gold
    Citation: Neurological Research and Practice 2020 2:30
    Content type: Letter to the editor Published on:

  38. Lumbar punctures are performed in different medical settings and are a key procedure in the diagnosis of several neurological conditions. Complications are rare and generally self-limiting. There are no report...

    Authors: Aleksander Fjeld Haugstvedt, Inger Birgitte Havsteen and Hanne Christensen
    Citation: Neurological Research and Practice 2020 2:36
    Content type: Letter to the editor Published on:

  39. After the end of Nazi terrorism with many crimes against neuropsychiatric and disabled people, from 1950 on detection and treatment of these diseases in children and adolescents grew continuously: in the 50s a...

    Authors: Hans Michael Strassburg
    Citation: Neurological Research and Practice 2020 2:28
    Content type: Review Published on:

  40. Postural control is a very important function in everyday life. However, assessing postural control with commonly used measurement instruments (MIs) is limited due to deficits in their psychometric properties....

    Authors: Elena Cramer, Franziska Weber, Gilian Faro, Michael Klein, Dennis Willeke, Thomas Hering and Dörte Zietz
    Citation: Neurological Research and Practice 2020 2:27
    Content type: Research article Published on:

  41. Traditionally, cerebellar disorders including ataxias have been associated with deficits in motor control and motor learning. Since the 1980’s growing evidence has emerged that cerebellar diseases also impede ...

    Authors: Andreas Thieme, Sandra Roeske, Jennifer Faber, Patricia Sulzer, Martina Minnerop, Saskia Elben, Heike Jacobi, Kathrin Reetz, Imis Dogan, Miriam Barkhoff, Juergen Konczak, Elke Wondzinski, Mario Siebler, Oliver Mueller, Ulrich Sure, Jeremy D. Schmahmann…
    Citation: Neurological Research and Practice 2020 2:39
    Content type: Clinical trial protocol Published on:

  42. Cerebellar transcranial direct current stimulation (tDCS) is widely considered as a promising non-invasive tool to foster motor performance and learning in health and disease. The results of previous studies, ...

    Authors: M. Rauscher, F. Yavari, G. Batsikadze, N. Ludolph, W. Ilg, M. A. Nitsche, D. Timmann and K. M. Steiner
    Citation: Neurological Research and Practice 2020 2:38
    Content type: Research article Published on:

  46. It is still unclear, which physiotherapeutic approaches are most effective in stroke recovery. Vojta therapy is a type of physiotherapy that was originally developed for children and adolescents with cerebral ...

    Authors: Corina Epple, Barbara Maurer-Burkhard, Mari-Carmen Lichti and Thorsten Steiner
    Citation: Neurological Research and Practice 2020 2:23
    Content type: Research article Published on:

  48. The anatomical distribution of acute lacunar infarcts has mainly been studied for supratentorial lesions. In addition, little is known about the association with distinct stroke symptoms, not summarized as cla...

    Authors: Ewgenia Barow, Hans Pinnschmidt, Florent Boutitie, Alina Königsberg, Martin Ebinger, Matthias Endres, Jochen B. Fiebach, Jens Fiehler, Vincent Thijs, Robin Lemmens, Keith W. Muir, Norbert Nighoghossian, Salvador Pedraza, Claus Z. Simonsen, Christian Gerloff, Götz Thomalla…
    Citation: Neurological Research and Practice 2020 2:21
    Content type: Research article Published on:

  49. The targeted use of endovascular therapy (EVT), with or without intravenous thrombolysis (IVT) in acute large cerebral vessel occlusion stroke (LVOS) has been proven to be superior compared to IVT alone. Despi...

    Authors: Philipp Ettelt, Ilko L. Maier, Marlena Schnieder, Mathias Bähr, Daniel Behme, Marios-Nikos Psychogios and Jan Liman
    Citation: Neurological Research and Practice 2020 2:29
    Content type: Research article Published on:

  50. Peripheral neuropathy represents a spectrum of diseases with different etiologies. The most common causes are diabetes, exposure to toxic substances including alcohol and chemotherapeutics, immune-mediated con...

    Authors: Helmar C. Lehmann, Gilbert Wunderlich, Gereon R. Fink and Claudia Sommer
    Citation: Neurological Research and Practice 2020 2:20
    Content type: Standard operating procedure Published on:
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