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  1. Stroke is a severe complication of infective endocarditis (IE), associated with high rates of mortality. Data on how IE patients with and without stroke differ may help to improve understanding contributing me...

    Authors: H. Schuermann, R. von Rennenberg, C. Riegler, I. Rangus, S. Litmeier, J. F. Scheitz, W. Doehner, H. Audebert, T. B. Braemswig and C. H. Nolte
    Citation: Neurological Research and Practice 2024 6:22
    Content type: Research article Published on:

  2. Guillain-Barré Syndrome (GBS) is an autoimmune neuropathy. Antecedent infections have been seen to be significant triggering factors for developing GBS. Among them, arboviral infections are rapidly gaining imp...

    Authors: Sreelakshmi V., Amrita Pattanaik, Srilatha Marate, Reeta S Mani, Aparna R. Pai and Chiranjay Mukhopadhyay
    Citation: Neurological Research and Practice 2024 6:21
    Content type: Review Published on:

  3. Brain tumors and metastases account for approximately 10% of all status epilepticus (SE) cases. This study described the clinical characteristics, treatment, and short- and long-term outcomes of this population.

    Authors: Johanna K. Rickel, Daria Zeeb, Susanne Knake, Hans Urban, Jürgen Konczalla, Katharina J. Weber, Pia S. Zeiner, Axel Pagenstecher, Elke Hattingen, André Kemmling, Emmanouil Fokas, Sebastian Adeberg, Robert Wolff, Martin Sebastian, Tillmann Rusch, Michael W. Ronellenfitsch…
    Citation: Neurological Research and Practice 2024 6:19
    Content type: Research article Published on:

  4. The risk of seizure recurrence after a first unprovoked epileptic seizure is reported to be approximately 40%. Little is known about the recurrence risk after a first seizure in elderly patients, who may be at...

    Authors: Louise Linka, Benedikt Magnus, Nabard Faiz, Lena Habermehl, Panagiota-Eleni Tsalouchidou, Felix Zahnert, Leona Moeller, Kristina Krause, Susanne Knake and Katja Menzler
    Citation: Neurological Research and Practice 2024 6:20
    Content type: Research article Published on:

  5. An increasing use of newer antiseizure medication (ASM) such as SV2A ligand brivaracetam is observed. However, data on newer antiseizure medication and therapeutic drug monitoring during pregnancy is scarce.

    Authors: Wiebke Hahn, Leona Möller, Katja Menzler, Tobias Poeplau, Uwe Wagner and Susanne Knake
    Citation: Neurological Research and Practice 2024 6:17
    Content type: Research article Published on:

  6. Post-COVID-19 Syndrome (PCS) includes neurological manifestations, especially fatigue and cognitive deficits. Immune dysregulation, autoimmunity, endothelial dysfunction, viral persistence, and viral reactivat...

    Authors: Christiana Franke, Vanessa Raeder, Fabian Boesl, Benno Bremer, Lucas C. Adam, Ameli Gerhard, Irina Eckert, Anneke Quitschau, Anne Pohrt, Susen Burock, Lisa Bruckert, Carmen Scheibenbogen, Harald Prüß and Heinrich J. Audebert
    Citation: Neurological Research and Practice 2024 6:16
    Content type: Clinical trial protocol Published on:

  7. Parkinson’s disease (PD) is a neurodegenerative condition that is frequently associated with cognitive disorders. These can arise directly from the primary disease, or be triggered by external factors in susce...

    Authors: Christine Daniels, Jon Rodríguez-Antigüedad, Elisabeth Jentschke, Jaime Kulisevsky and Jens Volkmann
    Citation: Neurological Research and Practice 2024 6:14
    Content type: Review Published on:

  8. The COVID-19 pandemic has affected acute stroke care, resulting in a decrease in stroke admissions worldwide. We examined trends in stroke severity at hospital admission, including (1) probable need for rehabi...

    Authors: Matthias Hans Belau, Björn Misselwitz, Uta Meyding-Lamadé and Burc Bassa
    Citation: Neurological Research and Practice 2024 6:18
    Content type: Research article Published on:

  9. In Multiple Sclerosis (MS), patients´ characteristics and (bio)markers that reliably predict the individual disease prognosis at disease onset are lacking. Cohort studies allow a close follow-up of MS historie...

    Authors: Antonios Bayas, Ulrich Mansmann, Begum Irmak Ön, Verena S. Hoffmann, Achim Berthele, Mark Mühlau, Markus C. Kowarik, Markus Krumbholz, Makbule Senel, Verena Steuerwald, Markus Naumann, Julia Hartberger, Martin Kerschensteiner, Eva Oswald, Christoph Ruschil, Ulf Ziemann…
    Citation: Neurological Research and Practice 2024 6:15
    Content type: Clinical trial protocol Published on:

  10. Repetitive traumatic brain injuries in American football players (AFPs) can lead to the neurodegenerative disease chronic traumatic encephalopathy (CTE). Clinical symptoms of CTE range from mood and behavioral...

    Authors: Theres Bastgen, Janis Evers, Christiane Oedekoven, Caroline Weide, Lars Herzog, Nicholas Ashton, Henrik Zetterberg, Kaj Blennow, Alexandra Albus, Natasha Vidovic, Oliver Kraff, Cornelius Deuschl, Richard Dodel and J. Alexander Ross
    Citation: Neurological Research and Practice 2024 6:13
    Content type: Research article Published on:

  11. 5q-associated spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis (ALS) are two distinct neurological disorders leading to degeneration of lower motor neurons. The antisense oligonucleotides (ASOs)...

    Authors: Maximilian Vidovic, Mario Menschikowski, Maren Freigang, Hanna Sophie Lapp and René Günther
    Citation: Neurological Research and Practice 2024 6:11
    Content type: Letter to the editor Published on:

  12. Novel treatments are needed to control refractory status epilepticus (SE). This study aimed to assess the potential effectiveness of fenfluramine (FFA) as an acute treatment option for SE. We present a summary...

    Authors: Adam Strzelczyk, Hendrik Becker, Lisa Tako, Susanna Hock, Elke Hattingen, Felix Rosenow and Catrin Mann
    Citation: Neurological Research and Practice 2024 6:10
    Content type: Research article Published on:

  13. Patients with Parkinson’s disease (PD) have been reported to exhibit unusual bouts of creativity (e.g., painting, writing), in particular in the context of treatment with dopaminergic agents. Here we investiga...

    Authors: Marcus Heldmann, Celia Rinckens, Norbert Brüggemann, Mohamed Al-Khaled and Thomas F. Münte
    Citation: Neurological Research and Practice 2024 6:9
    Content type: Research article Published on:

  14. While subthalamic nucleus deep brain stimulation (STN-DBS) improves the quality of life (QoL) of patients with Parkinson’s disease (PD), the clinical parameters that predict this improvement remain debated. Th...

    Authors: Carolin Semmler, Vasilija Stopic, Stefanie T. Jost, Gereon R. Fink, Peter H. Weiss and Michael T. Barbe
    Citation: Neurological Research and Practice 2024 6:8
    Content type: Research article Published on:

  15. Acquired brain injuries are among the most common causes of disability in adulthood. An intensive rehabilitation phase is crucial for recovery. However, there is a lack of concepts to further expand the therap...

    Authors: Mareike Schrader, Annette Sterr, Tobias Strank, Stephan Bamborschke and Christian Dohle
    Citation: Neurological Research and Practice 2024 6:7
    Content type: Research article Published on:

  16. Endovascular thrombectomy (EVT) is the most effective treatment for acute ischemic stroke caused by large vessel occlusion (LVO). Yet, long-term outcome (LTO) and health-related quality of life (HRQoL) in thes...

    Authors: Andreas Rogalewski, Nele Klein, Anja Friedrich, Alkisti Kitsiou, Marie Schäbitz, Frédéric Zuhorn, Burkhard Gess, Björn Berger, Randolf Klingebiel and Wolf-Rüdiger Schäbitz
    Citation: Neurological Research and Practice 2024 6:2
    Content type: Research article Published on:

  17. The diagnosis of neurosarcoidosis (NS) remains challenging due to the difficulty to obtain central nervous system (CNS) biopsies. Various diagnostic parameters are considered for the definition of possible, pr...

    Authors: Jessy Chen, Giulia Metzger, Christian Furth, Georg Bohner and Volker Siffrin
    Citation: Neurological Research and Practice 2024 6:12
    Content type: Letter to the editor Published on:

  19. Status epilepticus in pregnancy (SEP) is rare and life-threatening for both mother and fetus. There are well-established guidelines for the management of women with epilepsy during pregnancy; however, there is...

    Authors: Dionne Swor, Pallavi Juneja, Charlotte Constantine, Catrin Mann, Felix Rosenow and Suzette LaRoche
    Citation: Neurological Research and Practice 2024 6:3
    Content type: Research article Published on:

  20. The strengthening of interdisciplinary care collaboration in Parkinson's disease is taking on increasing importance in daily medical routine. Therefore, care providers worldwide are organizing themselves in di...

    Authors: Carina Lummer, Carsten Eggers, Andreas Becker, Fenja Demandt and Tobias Warnecke
    Citation: Neurological Research and Practice 2024 6:5
    Content type: Research article Published on:

  21. The treatment of ischemic stroke (IS) has changed considerably in recent years. Particularly the advent of mechanical thrombectomy (MTE) has revolutionized the available treatment options. Most patients in dev...

    Authors: Matthias N. Ungerer, Dirk Bartig, Daniel Richter, Christos Krogias, Werner Hacke and Christoph Gumbinger
    Citation: Neurological Research and Practice 2024 6:4
    Content type: Research article Published on:

  22. Corticobasal syndrome (CBS) is a clinical syndrome determined by various underlying neurodegenerative disorders requiring a pathological assessment for a definitive diagnosis. A literature review was performed...

    Authors: Giulia Remoli, Edoardo Dalmato Schilke, Andrea Magi, Antonio Ancidoni, Giulia Negro, Fulvio Da Re, Maura Frigo, Martina Giordano, Nicola Vanacore, Marco Canevelli, Carlo Ferrarese, Lucio Tremolizzo and Ildebrando Appollonio
    Citation: Neurological Research and Practice 2024 6:1
    Content type: Review Published on:

  23. In sepsis-associated critical illness neuromyopathy (CIPNM) serial electrical stimulation of motor nerves induces a short-lived temporary recovery of compound muscle action potentials (CMAPs) termed facilitati...

    Authors: Madona Sekhniashvili, Petra Baum and Klaus V. Toyka
    Citation: Neurological Research and Practice 2023 5:66
    Content type: Research article Published on:

  24. Endovascular stroke treatment (EST) has become the standard treatment for patients with stroke due to large vessel occlusion, especially in earlier time windows. Only few data from population-based registries ...

    Authors: Sonja Hyrenbach, Susanne Rode, Martin Schabet, Michael Daffertshofer, Karin Schoser, Stephan Neumaier and Peter A. Ringleb
    Citation: Neurological Research and Practice 2023 5:67
    Content type: Research article Published on:

  25. Epilepsy surgery is an established treatment for drug-resistant focal epilepsy (DRFE) that results in seizure freedom in about 60% of patients. Correctly identifying an epileptogenic lesion in magnetic resonan...

    Authors: Leonhard Mann, Felix Rosenow, Adam Strzelczyk, Elke Hattingen, Laurent M. Willems, Patrick N. Harter, Katharina Weber and Catrin Mann
    Citation: Neurological Research and Practice 2023 5:65
    Content type: Research article Published on:

  26. Endovascular thrombectomy (EVT) is highly effective in acute stroke patients with intracranial large vessel occlusion (LVO), however, presence of concomitant cervical occlusion of the internal carotid artery (...

    Authors: Norma J. Diel, Stefan T. Gerner, Omar Alhaj Omar, Johannes Kalder, Enikö Manz, Paula R. Keschenau, Tobias Struffert, Thomas Brueckner, Hagen B. Huttner and Thorsten R. Doeppner
    Citation: Neurological Research and Practice 2023 5:60
    Content type: Research article Published on:

  27. The modified Rankin scale (mRS) at 3 months is established as the primary outcome measure in clinical stroke trials. Traditionally, the mRS is assessed through an unstructured face-to-face interview. This appr...

    Authors: Lennart Steffen Milles, Doreen Pommeranz, Woon Hyung Chae, Jordi Kühne Escolà, Christoph Kleinschnitz, Martin Köhrmann and Benedikt Frank
    Citation: Neurological Research and Practice 2023 5:59
    Content type: Research article Published on:

  28. Choreiform movement disorders are characterized by involuntary, rapid, irregular, and unpredictable movements of the limbs, face, neck, and trunk. These movements often initially go unnoticed by the affected i...

    Authors: Carsten Saft, Jean-Marc Burgunder, Matthias Dose, Hans Heinrich Jung, Regina Katzenschlager, Josef Priller, Huu Phuc Nguyen, Kathrin Reetz, Ralf Reilmann, Klaus Seppi and Georg Bernhard Landwehrmeyer
    Citation: Neurological Research and Practice 2023 5:63
    Content type: Guidelines Published on:

  29. Ameliorating symptoms and signs of Huntington’s disease (HD) is essential to care but can be challenging and hard to achieve. The pharmacological treatment of motor signs (e.g. chorea) may favorably or unfavor...

    Authors: Carsten Saft, Jean-Marc Burgunder, Matthias Dose, Hans Heinrich Jung, Regina Katzenschlager, Josef Priller, Huu Phuc Nguyen, Kathrin Reetz, Ralf Reilmann, Klaus Seppi and Georg Bernhard Landwehrmeyer
    Citation: Neurological Research and Practice 2023 5:61
    Content type: Guidelines Published on:

  30. Evaluation of outcome after stroke is largely based on assessment of gross function 3 months after stroke onset using scales such as mRS. Cognitive or social functions, level of symptom burden or emotional hea...

    Authors: Marie Schäbitz, Leona Möller, Anja Friedrich, Nele Klein, Alkisti Kitsiou, Isabell Greeve, Anja Gerstner, Leonard Wulff, Wolf-Rüdiger Schäbitz, Lars Timmermann and Andreas Rogalewski
    Citation: Neurological Research and Practice 2023 5:62
    Content type: Research article Published on:

  31. Authors: Dirk Sander, Thorsten Bartsch, Florian Connolly, Christian Enzinger, Urs Fischer, Nils Nellessen, Holger Poppert, Kristina Szabo and Helge Topka
    Citation: Neurological Research and Practice 2023 5:64
    Content type: Correction Published on:

    The original article was published in Neurological Research and Practice 2023 5:15

  32. As a complication of subarachnoid hemorrhage (SAH), vasospasm substantially contributes to its morbidity and mortality. We aimed at analyzing predictors of outcome for these patients including the role of endo...

    Authors: Sina Burth, Jan Meis, Dorothea Kronsteiner, Helena Heckhausen, Klaus Zweckberger, Meinhard Kieser, Wolfgang Wick, Christian Ulfert, Markus Möhlenbruch, Peter Ringleb and Silvia Schönenberger
    Citation: Neurological Research and Practice 2023 5:57
    Content type: Research article Published on:

  33. Fetal acetylcholine receptor antibody-associated disorders (FARAD), caused by in utero exposure to maternal antibodies directed against the fetal acetylcholine receptor (AChR), is a rare condition occurring in...

    Authors: Matthias Wassenberg, Andreas Hahn, Anna Mück and Heidrun H. Krämer
    Citation: Neurological Research and Practice 2023 5:58
    Content type: Letter to the editor Published on:

  34. Diffuse midline gliomas (DMG) are universally lethal central nervous system tumors that carry almost unanimously the clonal driver mutation histone-3 K27M (H3K27M). The single amino acid substitution of lysine...

    Authors: Niklas Grassl, Katharina Sahm, Heike Süße, Isabel Poschke, Lukas Bunse, Theresa Bunse, Tamara Boschert, Iris Mildenberger, Anne-Kathleen Rupp, Max Philipp Ewinger, Lisa-Marie Lanz, Monika Denk, Ghazaleh Tabatabai, Michael W. Ronellenfitsch, Ulrich Herrlinger, Martin Glas…
    Citation: Neurological Research and Practice 2023 5:55
    Content type: Clinical trial protocol Published on:

  35. As the clinical differentiation between epileptic seizures, psychogenic non-epileptic seizures (PNES), and syncope depends mainly on a detailed report of the event, which may not be available, an objective ass...

    Authors: Ramy Abdelnaby, Anas Elgenidy, Jan Heckelmann, Mahmoud Mostafa Bedewy, Ahmed Samy Shabib, Mohamed Ayman Ebrahim, Khaled Abdelmoneim Elmenawi, Imene Maallem, Merna Wagih Youssef, Abdelrahman M. Attia, Mostafa Hossam Moawad, Khaled Ashraf Mohamed and Ahmed Gaballa
    Citation: Neurological Research and Practice 2023 5:56
    Content type: Review Published on:

  36. Causal therapies are not yet available for most neuromuscular diseases. Additionally, data on the use of complementary or alternative therapies (CAM) in patients groups with a variety of different neuromuscula...

    Authors: Lene Änne Böhne, Corinna Wirner, Benedikt Schoser, Carsten Schröter and Petra Baum
    Citation: Neurological Research and Practice 2023 5:53
    Content type: Research article Published on:

  37. Embolic stroke of undetermined source (ESUS) accounts for a substantial proportion of ischaemic strokes. A stroke recurrence score has been shown to predict the risk of recurrent stroke in patients with ESUS b...

    Authors: Thies Ingwersen, Manuel C. Olma, Eckhard Schlemm, Carola Mayer, Bastian Cheng, Serdar Tütüncü, Paulus Kirchhof, Roland Veltkamp, Joachim Röther, Ulrich Laufs, Darius G. Nabavi, George Ntaios, Matthias Endres, Karl Georg Haeusler and Götz Thomalla
    Citation: Neurological Research and Practice 2023 5:51
    Content type: Research article Published on:

  38. Headache is one of the most common neurological manifestations of COVID-19, but it is unclear whether chronic headache as a symptom of Post-COVID-19 is associated with ongoing CNS damage. We compared cerebrosp...

    Authors: Laura de Boni, Alexandru Odainic, Natalie Gancarczyk, Luisa Kaluza, Christian P. Strassburg, Xenia A. K. Kersting, Ullrich Wüllner, Susanne V. Schmidt and Gabor C. Petzold
    Citation: Neurological Research and Practice 2023 5:49
    Content type: Letter to the editor Published on:

  39. This letter to the editor discusses “the use of video-EEG monitoring to guide antiseizure medication (ASM) withdrawal in patients with epilepsy” [1]. The author highlights the potential benefits of this approach,...

    Authors: Obed Okwoli Apochi
    Citation: Neurological Research and Practice 2023 5:47
    Content type: Letter to the editor Published on:

    The original article was published in Neurological Research and Practice 2023 5:20

  41. Patients with an intensive care unit-acquired weakness (ICU-AW) often present clinically with severe paresis of the limb and trunk muscles while facial muscles appear less affected. To investigate whether the ...

    Authors: Maximilian Lochter, Martin Sommer, Onnen Moerer and Caspar Stephani
    Citation: Neurological Research and Practice 2023 5:50
    Content type: Research article Published on:

  42. Cognitive decline is a major factor for the deterioration of the quality of life in patients suffering from Parkinson’s disease (PD). Recently, it was reported that cognitive training (CT) in PD patients with ...

    Authors: Carlos Trenado, Paula Trauberg, Saskia Elben, Karina Dimenshteyn, Ann-Kristin Folkerts, Karsten Witt, Daniel Weiss, Inga Liepelt-Scarfone, Elke Kalbe and Lars Wojtecki
    Citation: Neurological Research and Practice 2023 5:46
    Content type: Research article Published on:

  44. The aim of this study was to examine in patients with idiopathic and neurodegenerative normal pressure hydrocephalus (NPH) if motor and cognitive performance as well as changes in biomarkers in cerebrospinal f...

    Authors: Leonard L. Klemke, Katharina Müller-Schmitz, Aschwin Kolman and Rüdiger J. Seitz
    Citation: Neurological Research and Practice 2023 5:52
    Content type: Research article Published on:

  46. The incidence of community-acquired acute bacterial meningitis has decreased during the last decades. However, outcome remains poor with a significant proportion of patients not surviving and up to 50% of surv...

    Authors: Matthias Klein, Carsten Abdel-Hadi, Robert Bühler, Beatrice Grabein, Jennifer Linn, Roland Nau, Bernd Salzberger, Dirk Schlüter, Konrad Schwager, Hayrettin Tumani, Jörg Weber and Hans-Walter Pfister
    Citation: Neurological Research and Practice 2023 5:44
    Content type: Guidelines Published on:

  47. Chronic inflammatory demyelinating polyneuropathy (CIDP) is one of the most common immune neuropathies leading to severe impairments in daily life. Current treatment options include intravenous immunoglobulins...

    Authors: Lars Masanneck, Jan Voth, Niklas Huntemann, Menekse Öztürk, Christina B. Schroeter, Tobias Ruck, Sven G. Meuth and Marc Pawlitzki
    Citation: Neurological Research and Practice 2023 5:39
    Content type: Clinical trial protocol Published on:

  48. In a retrospective study, the data of direction-dependent deviations in dynamic subjective visual vertical (SVV) testing were analysed in 1811 dizzy patients (174 benign paroxysmal positional vertigo, 99 unilater...

    Authors: Johannes Gerb, Lena Padovan, Nicole Lehrer, Thomas Brandt and Marianne Dieterich
    Citation: Neurological Research and Practice 2023 5:37
    Content type: Letter to the editor Published on:

  49. Immunological alterations associated with increased susceptibility to infection are an essential aspect of stroke pathophysiology. Several immunological functions of adipose tissue are altered by obesity and a...

    Authors: Johanna Ruhnau, Christin Heuer, Carl Witt, Sonya Ceesay, Juliane Schulze, Stefan Gross, Maria Waize, Marie-Luise Kromrey, Jens-Peter Kühn, Sönke Langner, Uwe Grunwald, Barbara M. Bröker, Astrid Petersmann, Antje Steveling, Alexander Dressel and Antje Vogelgesang
    Citation: Neurological Research and Practice 2023 5:42
    Content type: Research article Published on:

  50. Cerebral vasculopathies frequently lead to severe medical conditions such as stroke or intracranial hemorrhage and have a broad range of possible etiologies that require different therapeutic regimens. However...

    Authors: Jan K. Focke and Markus Kraemer
    Citation: Neurological Research and Practice 2023 5:38
    Content type: Research article Published on:
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